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Halofantrine

API Standards
CAT No.
:
CS-O-01632

CAS No.

:

69756-53-2

Molecular Weight

:

500.42

Molecular Formula

:

C26H3Cl2F3NO

Purity

:

>98%

Inventory Status:

:

Available for Immediate Shipment
 

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Useful information

"Halofantrine is a drug used to treat malaria. Halofantrine's structure contains a substituted phenanthrene, and is related to the antimalarial drugs quinine and lumefantrine. Marketed as Halfan, halofantrine is never used to prevent malaria and its mode of action is unknown, although a crystallographic study showed that it binds to hematin in vitro, suggesting a possible mechanism of action. Halofantrine has also been shown to bind to plasmpesin, a haemoglobin degrading enzyme unique to the malarial parasites.

Halofantrine was developed at SRI International for the Walter Reed Army Institute of Research from 1965 to 1975 by a team led by medicinal chemist William Colwell.",""



Product Application Notes

NA



References

de Villiers KA, Marques HM, Egan TJ (2008); Friedman R, Caflisch A (2009)



MSDS



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This page contains information about Halofantrine Cas # 69756-53-2 and its API Standards.

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Keywords

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Related result for 'Halofantrine'

- Halofantrine : API Standards

- Halofantrine : Stable Isotopes

- Halofantrine : Metabolites

- Halofantrine : Impurities



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