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"Halofantrine is a drug used to treat malaria. Halofantrine's structure contains a substituted phenanthrene, and is related to the antimalarial drugs quinine and lumefantrine. Marketed as Halfan, halofantrine is never used to prevent malaria and its mode of action is unknown, although a crystallographic study showed that it binds to hematin in vitro, suggesting a possible mechanism of action. Halofantrine has also been shown to bind to plasmpesin, a haemoglobin degrading enzyme unique to the malarial parasites.
Halofantrine was developed at SRI International for the Walter Reed Army Institute of Research from 1965 to 1975 by a team led by medicinal chemist William Colwell.",""
de Villiers KA, Marques HM, Egan TJ (2008); Friedman R, Caflisch A (2009)
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This page contains information about Halofantrine Cas # 69756-53-2 and its API Standards.
Halofantrine Halofantrine Worldwide Suppliers of Halofantrine https://www.clearsynth.com/en/CSO01632.html API Standards Clearsynth 69756-53-2
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Keywords: API Standards CS-O-01632 Halofantrine Halofantrine 69756-53-2 500.42 C26H3Cl2F3NO
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