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Hydroxy Bosentan D6

Stable Isotopes
CAT No.
:
CS-O-02698

CAS No.

:

1246817-57-1

Molecular Weight

:

573.65

Molecular Formula

:

C27H23D6N5O7S

Purity

:

97.68 %

Inventory Status:

:

Available for Immediate Shipment

HS Code:

:

28459090

 

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1,600.00 / 10mg

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2,400.00 / 25mg

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Useful information

"Bosentan is a dual endothelin receptor antagonist used in the treatment of pulmonary artery hypertension (PAH). It is licensed in the United States, the European Union and other countries by Actelion Pharmaceuticals for the management of PAH under the trade name Tracleer.",""



Product Application Notes

A labelled analogue of the active metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator.;Labeled Bosentan, intended for use as an internal standard for the quantification of Bosentan by GC- or LC-mass spectrometry.



Synonyms

4-[2-Hydroxy-1,1-(dimethyl-d6)ethyl]-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634-d6; Ro 48-5033-d6



References

Clozel, M., et al.: J. Pharmcol. Exp. Ther., 270, 228 (1994), Gutch, G., et al.:cardiovac. Drugs Ther., 10, 717 (1996), Weber,c., et al.:clin Pharmcol. Ther., 60, 124 (1996), Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998)



MSDS



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This page contains information about Hydroxy Bosentan D6 Cas # 1246817-57-1 and its Stable Isotopes.

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  1. Stable Isotopes

  2. Hydroxy Bosentan D6



Keywords

Keywords: Stable Isotopes 4-[2-Hydroxy-1,1-(dimethyl-d6)ethyl]-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634-d6; Ro 48-5033-d6 CS-O-02698 Hydroxy Bosentan D6 Bosentan 1246817-57-1 573.65 C27H23D6N5O7S
Internal standard, Internal standard Bosentan, HPLC-MS method validation, HPLC-MS method validation Bosentan, LC-MS-MS method validation, LC-MS-MS method validation Bosentan, Deuterated internal standard, Deuterated internal standard Bosentan, Deuterated Bosentan, Deuterium labeled Bosentan, Quantitative bioanalytical methods, Quantitative bioanalytical methods Bosentan, Blood samples Bosentan, Blood concentrations, Heavy drugs, Analysis, Analysis Bosentan, Clinical diagnostic, Clinical diagnostic Bosentan, Dosing Bosentan, Analytical method development, Internal standard method.



Related result for 'Hydroxy Bosentan D6'

- Bosentan : API Standards

- Bosentan : Stable Isotopes

- Bosentan : Metabolites

- Bosentan : Impurities

- Bosentan : Intermediates



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