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HygroCopC,-20°C Freezer, Under Inert Atmosphere
"Guanfacine (brand name Estulic, Tenex and the extended release Intuniv; not to be confused with guaifenesin, an expectorant) is a sympatholytic drug used in the treatment of attention deficit hyperactivity disorder (ADHD), anxiety, and hypertension. It is a selective ⓬A receptor agonist. These receptors are concentrated heavily in the prefrontal cortex and the locus coeruleus, with the potential to improve attention resulting from interaction with receptors in the former. Guanfacine lowers both systolic and diastolic blood pressure by activating the central nervous system ⓬A norepinephrine autoreceptors, which results in reduced peripheral sympathetic outflow and thus a reduction in peripheral sympathetic tone.
Guanfacine is currently approved and marketed in the United States and Europe as Intuniv for the treatment of ADHD in children and adolescents aged 6\u201318 years.",""
Labeled Guanfacine, intended for use as an internal standard for the quantification of Guanfacine by GC- or LC-mass spectrometry.
Urosevic, D., et al.: Br. J. Pharmacol., 142, 609 (2004), Remko, M., et al.: Bioorg. Med. Chem., 14, 1715 (2006), Nikolic, K., et al.: Bioorg. Med. Chem., 16, 7134 (2008).
We normally respond within 8 hours.
This page contains information about Guanfacine 13C 15N3 Cas # 1189924-28-4 and its Stable Isotopes.
Guanfacine 13C 15N3 Guanfacine 13C 15N3 Worldwide Suppliers of Guanfacine 13C 15N3 https://www.clearsynth.com/en/CSO03035.html Stable Isotopes Clearsynth 1189924-28-4
Product rating: 9 Guanfacine 13C 15N3 based on 20 ratings
Keywords: Guanfacine 13C 15N3, CS-O-03035, 1189924-28-4, , C8[13C]H9Cl2[15N]3O, 250.06, Labeled Guanfacine, intended for use as an internal standard for the quantification of Guanfacine by GC- or LC-mass spectrometry.
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