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Guanfacine 13C 15N3

Stable Isotopes
CAT No.
:
CS-O-03035

CAS No.

:

1189924-28-4

Molecular Weight

:

250.06

Molecular Formula

:

C8[13C]H9Cl2[15N]3O

Purity

:

99.6 %

Long Term Storage

:

HygroCopC,-20°C Freezer, Under Inert Atmosphere

Appearance

:

White Solid

HS Code:

:

28459090

 


Useful information

"Guanfacine (brand name Estulic, Tenex and the extended release Intuniv; not to be confused with guaifenesin, an expectorant) is a sympatholytic drug used in the treatment of attention deficit hyperactivity disorder (ADHD), anxiety, and hypertension. It is a selective ⓬A receptor agonist. These receptors are concentrated heavily in the prefrontal cortex and the locus coeruleus, with the potential to improve attention resulting from interaction with receptors in the former. Guanfacine lowers both systolic and diastolic blood pressure by activating the central nervous system ⓬A norepinephrine autoreceptors, which results in reduced peripheral sympathetic outflow and thus a reduction in peripheral sympathetic tone.

Guanfacine is currently approved and marketed in the United States and Europe as Intuniv for the treatment of ADHD in children and adolescents aged 6\u201318 years.",""



Product Application Notes

Labeled Guanfacine, intended for use as an internal standard for the quantification of Guanfacine by GC- or LC-mass spectrometry.



References

Urosevic, D., et al.: Br. J. Pharmacol., 142, 609 (2004), Remko, M., et al.: Bioorg. Med. Chem., 14, 1715 (2006), Nikolic, K., et al.: Bioorg. Med. Chem., 16, 7134 (2008).



MSDS



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This page contains information about Guanfacine 13C 15N3 Cas # 1189924-28-4 and its Stable Isotopes.

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Keywords

Keywords: Guanfacine 13C 15N3, CS-O-03035, 1189924-28-4, , C8[13C]H9Cl2[15N]3O, 250.06, Labeled Guanfacine, intended for use as an internal standard for the quantification of Guanfacine by GC- or LC-mass spectrometry.
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Related result for 'Guanfacine 13C 15N3'

- Guanfacine : API Standards

- Guanfacine : Stable Isotopes

- Guanfacine : Metabolites

- Guanfacine : Impurities

- Guanfacine : Glucuronides



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