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"Paclitaxel (PTX), sold under the brand name Taxol among others, is a chemotherapy medication used to treat a number of types of cancer. This includes ovarian cancer, breast cancer, lung cancer, Kaposi sarcoma, cervical cancer, and pancreatic cancer. It is given by injection into a vein. There is also an albumin bound formulation.
Common side effects include hair loss, bone marrow suppression, numbness, allergic reactions, muscle pains, and diarrhea. Other serious side effects include heart problems, increased risk of infection, and lung inflammation. There are concerns that use during pregnancy may cause birth defects. Paclitaxel is in the taxane family of medications. It works by interference with the normal function of microtubules during cell division.
Paclitaxel was first isolated in 1971 from the Pacific yew and approved for medical use in 1993. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. The wholesale cost in the developing world is about 7.06 to 13.48 USD per 100 mg vial. This amount in the United Kingdom costs the NHS about 66.85 pounds. It is now manufactured by cell culture.",""
Impurity in commercial preparation of Paclitaxel.
7-Epi 10-Desacetyl Paclitaxel;USP Paclitaxel Related Compound B;10-epitaxol; 10-Dtaxel; 7-Epi-10-decetyltaxol; 7-epi-10-Decetyltaxol; Ormosin VI; USP Pclitaxel Relatedcompound B;
chiff, P., et al.: Nature, 277, 665 (1979), Parness, J., et al.: J.cell Biol., 91, 479 (1981), Swindell,c., et al.: J. Med.chem., 34, 1176 (1991), Dordunoo, S., et al.: Int. J. Pharm., 133, 191 (1996), Ueda, J., et al.: Planta Med. Epub (2006),
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This page contains information about 7-Epi 10-Desacetyl Paclitaxel Cas # 78454-17-8 and its Impurities.
7-Epi 10-Desacetyl Paclitaxel 7-Epi 10-Desacetyl Paclitaxel Worldwide Suppliers of 7-Epi 10-Desacetyl Paclitaxel https://www.clearsynth.com/en/CSO05483.html Impurities Clearsynth 78454-17-8
Regular price: $1000 In stock
Product rating: 9 7-Epi 10-Desacetyl Paclitaxel based on 20 ratings
Keywords: Impurities 7-Epi 10-Desacetyl Paclitaxel;USP Paclitaxel Related Compound B;10-epitaxol; 10-Dtaxel; 7-Epi-10-decetyltaxol; 7-epi-10-Decetyltaxol; Ormosin VI; USP Pclitaxel Relatedcompound B; CS-O-05483 7-Epi 10-Desacetyl Paclitaxel Paclitaxel 78454-17-8 811.87 C45H49NO13
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