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"Ceritinib (INN, trade name Zykadia /za\u026a\u02c8ke\u026adi\u02d0\u0259/ zy-KAY-dee-\u0259) is a drug for the treatment of a specific type of lung cancer. It is an anaplastic lymphoma kinase (ALK) inhibitor. It was developed by Novartis. It was approved in April 2014 by the Food and Drug Administration for the treatment of ALK-positive metastatic non-small cell lung cancer (NSCLC) in patients that failed treatment with crizotinib. It is a more effective, but more toxic, alternative to traditional platinum-based chemotherapies.
Ceritinib is used for the treatment of adults with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) following failure (secondary to resistance or intolerance) of prior crizotinib therapy.
Medscape. April 29, 2014; Engelman JA (2014)
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This page contains information about Ceritinib Cas # 1032900-25-6 and its API Standards.
Ceritinib Ceritinib Worldwide Suppliers of Ceritinib https://www.clearsynth.com/en/CSO11185.html API Standards Clearsynth 1032900-25-6
Product rating: 9 Ceritinib based on 20 ratings
Keywords: API Standards 5chloro-N2-(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)-N4-(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine CS-O-11185 Ceritinib Ceritinib 1032900-25-6 558.14 C28H3ClN5O3S
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