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Aflibercept

API Standards
CAT No.
:
CS-O-11214

CAS No.

:

862111-32-8

Molecular Weight

:

6856.9

Molecular Formula

:

C308H495N79O91S3

Purity

:

>98%

 


Useful information

"Aflibercept (INN, USAN) is a biopharmaceutical drug invented by Regeneron Pharmaceuticals, approved in the United States and Europe for the treatment of wet macular degeneration under the trade name Eylea, and for metastatic colorectal cancer as Zaltrap. As the active ingredient of Zaltrap, the substance is called ziv-aflibercept in the US.

It is an inhibitor of vascular endothelial growth factor (VEGF).

Aflibercept is being co-developed for cancer treatment by Sanofi and Regeneron under a deal signed in 2003, and is being co-developed for eye diseases by Bayer HealthCare and Regeneron under a deal signed in 2006.",""



Product Application Notes

It is an inhibitor of vascular endothelial growth factor.



Synonyms

seryl-α-aspartylthreonylglycylarginylprolylphenylalanylvalyl-α-glutamylmethionyltyrosylseryl-α-glutamylisoleucylprolyl-α-glutamylisoleucylisoleucylhistidylmethionylthreonyl-α-glutamylglycylarginyl-α-glutamylleucylvalylisoleucylprolylcysteinylarginylvalylthreonylserylprolylasparagylisoleucylthreonylvalylthreonylleucyllysyllysylphenylalanylprolylleucyl-α-aspartylthreonylleucylisoleucylprolyl-α-aspartylglycyllysylarginylisoleucylisoleucyltryptophyl-α-aspartylserine



References

Wiegand SJ (May 2008); Fraser ;HM (July 2008)



MSDS



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Page info:

This page contains information about Aflibercept Cas # 862111-32-8 and its API Standards.

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Keywords

Keywords: API Standards seryl-α-aspartylthreonylglycylarginylprolylphenylalanylvalyl-α-glutamylmethionyltyrosylseryl-α-glutamylisoleucylprolyl-α-glutamylisoleucylisoleucylhistidylmethionylthreonyl-α-glutamylglycylarginyl-α-glutamylleucylvalylisoleucylprolylcysteinylarginylvalylthreonylserylprolylasparagylisoleucylthreonylvalylthreonylleucyllysyllysylphenylalanylprolylleucyl-α-aspartylthreonylleucylisoleucylprolyl-α-aspartylglycyllysylarginylisoleucylisoleucyltryptophyl-α-aspartylserine CS-O-11214 Aflibercept Aflibercept 862111-32-8 6856.9 C308H495N79O91S3
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- Aflibercept : API Standards



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