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Crofelemer

API Standards
CAT No.
:
CS-O-11215

CAS No.

:

148465-45-6

Molecular Weight

:

857.83

Molecular Formula

:

C15O6,7H12)n

Purity

:

>98%

 


Useful information

"Crofelemer (USAN, trade name Mytesi) is a botanical drug for the treatment of diarrhoea associated with anti-HIV drugs such as nucleoside analog reverse transcriptase inhibitors and protease inhibitors. Other possible uses include diarrhoea in children, acute infectious diarrhoea, and diarrhoea in patients with irritable bowel syndrome. It is a purified oligomeric proanthocyanidin from \"dragon's blood\", the sap of the South American tree Croton lechleri.

Crofelemer treats the symptoms of disease, but it is not used to treat infectious diarrhoea (diarrhoea caused by infection of the digestive system by a bacterium, virus or parasite).

It was initially developed by Napo Pharmaceuticals, which licensed it to Glenmark Pharmaceuticals in 140 emerging markets and to Salix Pharmaceuticals in the US, EU and some other markets. A Phase III clinical trial for diarrhoea in HIV patients was completed in 2012, and the drug was approved by the US Food and Drug Administration (FDA) on 31 December 2012.",""



Product Application Notes

Crofelemer is a drug under development for the treatment of diarrhea associated with anti-HIV drugs such as nucleoside analog reverse transcriptase inhibitors and protease inhibitors. Other possible uses include diarrhea in children, acute infectious diarrhea.



References

Verkman, A. S. (2009); H. Spreitzer (10 September 2012)



MSDS



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This page contains information about Crofelemer Cas # 148465-45-6 and its API Standards.

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Keywords

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- Crofelemer : API Standards



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