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Grazoprevir

API Standards
CAT No.
:
CS-O-12024

CAS No.

:

1350514-68-9

Molecular Weight

:

766.9

Molecular Formula

:

C38H50N6O9S

Purity

:

99.3 %

Long Term Storage

:

2-8°C

 


Useful information

"Grazoprevir is a drug approved for the treatment of hepatitis C. It was developed by Merck and completed Phase III trials, used in combination with the NS5A replication complex inhibitor elbasvir under the trade name Zepatier, either with or without ribavirin.

Grazoprevir is a second generation hepatitis C virus protease inhibitor acting at the NS3/4A protease targets. It has good activity against a range of HCV genotype variants, including some that are resistant to most currently used antiviral medications.",""



Product Application Notes

Grazoprevir is a second-generation protease inhibitor



Synonyms

Grazoprevir;1350514-68-9;(1aR,5S,8S,10R,22aR)-5-tert-butyl-N-((1R,2S)-1{[cclopropylsulfonyl)aminocarbonyl}-2-vinycclopropyl)-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradcahydro-8H-7,10-methancclopropa[18,19][1,10,3,6]dioxadiazcclononadcino[11,12-b]quinoxaline-8carboxamide;(1R,2S)-N-[[[(1R,2R)-2-[5-(3-Hydroxy-6-methoxy-2-quinoxalinyl)pentylcclopropyl]oxycarbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-N-cclopropylsulfonyl)-2-ethenycclopropancarboxamidecclc (1→2)-ether.



References

ACS Med Chem Lett. 2012;Expert Opinion on Investigational Drugs. 2014



MSDS



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This page contains information about Grazoprevir Cas # 1350514-68-9 and its API Standards.

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Keywords

Keywords: API Standards Grazoprevir;1350514-68-9;(1aR,5S,8S,10R,22aR)-5-tert-butyl-N-((1R,2S)-1{[cclopropylsulfonyl)aminocarbonyl}-2-vinycclopropyl)-14-methoxy-3,6-dioxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradcahydro-8H-7,10-methancclopropa[18,19][1,10,3,6]dioxadiazcclononadcino[11,12-b]quinoxaline-8carboxamide;(1R,2S)-N-[[[(1R,2R)-2-[5-(3-Hydroxy-6-methoxy-2-quinoxalinyl)pentylcclopropyl]oxycarbonyl]-3-methyl-L-valyl-(4R)-4-hydroxy-L-prolyl-1-amino-N-cclopropylsulfonyl)-2-ethenycclopropancarboxamidecclc (1→2)-ether. CS-O-12024 Grazoprevir Grazoprevir 1350514-68-9 766.9 C38H50N6O9S
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- Grazoprevir : API Standards



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