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"Alfacalcidol (or 1-hydroxycholecalciferol) is an analogue of vitamin D used for supplementation in humans and as a poultry feed additive.
Alfacalcidol has a weaker impact on calcium metabolism and parathyroid hormone levels than calcitriol, however alfacalcidol has significant effects on the immune system, including regulatory T cells. It is considered to be a more useful form of vitamin D supplementation, mostly due to much longer half-life and lower kidney load. It is the most commonly prescribed vitamin D metabolite for patients with end stage renal disease, given that impaired renal function alters the ability to carry out the second hydroxylation step required for the formation of the physiologically active form of vitamin D, 1,25-dihydroxyvitamin D3. Alfacalcidol is an active vitamin D3 metabolite, and therefore does not require the second hydroxylation step in the kidney.
Used as a poultry feed additive, it prevents tibial dyschondroplasia and increases phytate bioavailability.",""
Labeled Alfacalcidol , intended for use as an internal standard for the quantification of Alfacalcidol by GC- or LC-mass spectrometry.
5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyidene]ethylidene]-4-methylene-1d7; 1-a-Hydroxcholcaciferol-d7; 1-a-Hydroxyvitamin D3-d7; αrol-d7; α D3-d7; Etα-d7; Oxydevit-d7;
Autoimmunity Reviews, August 2010;Clin Cases Miner Bone Metab 6 (2): 169–173. 2009
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This page contains information about Alfacalcidol-d7 Cas # 41294-56-8(Unlabeled) and its Stable Isotopes.
Alfacalcidol-d7 Alfacalcidol-d7 Worldwide Suppliers of Alfacalcidol-d7 https://www.clearsynth.com/en/CSO13503.html Stable Isotopes Clearsynth 41294-56-8(Unlabeled)
Product rating: 9 Alfacalcidol-d7 based on 20 ratings
Keywords: Stable Isotopes 5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-Dimethylhexyidene]ethylidene]-4-methylene-1d7; 1-a-Hydroxcholcaciferol-d7; 1-a-Hydroxyvitamin D3-d7; αrol-d7; α D3-d7; Etα-d7; Oxydevit-d7; CS-O-13503 Alfacalcidol-d7 Alfacalcidol 41294-56-8(Unlabeled) 407.68 C27H37D7O2
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