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(4R)-Nicardipine Monomethyl ester

Impurities
CAT No.
:
CS-O-14765

CAS No.

:

NA

Molecular Weight

:

288.29

Molecular Formula

:

C15H16N2O4

Purity

:

>98%

HS Code:

:

29049090

 


Useful information

"Nicardipine hydrochloride (Cardene) is a medication used to treat high blood pressure and angina. It belongs to the dihydropyridine class of calcium channel blockers.

Nicardipine is a dihydropyridine calcium-channel blocking agent used for the treatment of vascular disorders such as chronic stable angina, hypertension, and Raynaud's phenomenon. It is available in oral and intravenous formulations. Its mechanism of action and clinical effects closely resemble those of nifedipine and the other dihydropyridines (amlodipine, felodipine), except that nicardipine is more selective for cerebral and coronary blood vessels. Nicardipine also has a longer half-life than nifedipine. Nicardipine was approved by the FDA in December 1988. The patent for both Cardene and Cardene SR expired in October 1995.

It has been used in percutaneous coronary intervention.",""



Product Application Notes

Impurity in commercial preparation of Nicardipine.



Synonyms

(R)-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3carboxylate.



References

Triggle, A., et al.: J. Med.chem., 23, 1442 (1980),



MSDS



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Keywords

Keywords: Impurities (R)-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3carboxylate. CS-O-14765 (4R)-Nicardipine Monomethyl ester Nicardipine NA 288.29 C15H16N2O4
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Related result for '(4R)-Nicardipine Monomethyl ester'

- Nicardipine : API Standards

- Nicardipine : Stable Isotopes

- Nicardipine : Metabolites

- Nicardipine : Impurities



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