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1,1,1,3,3-pentafluoro isopropenyl fluoromethyl ether

Impurities
CAT No.
:
CS-O-16090

CAS No.

:

58109-34-5

Molecular Weight

:

180.05

Molecular Formula

:

C4H2F6O

Purity

:

>98 %

HS Code:

:

29049090

 


Useful information

"Sevoflurane (1,1,1,3,3,3-hexafluoro-2-(fluoromethoxy)propane; synonym, fluoromethyl hexafluoroisopropyl ether), is a sweet-smelling, nonflammable, highly fluorinated methyl isopropyl ether used as an inhalational anaesthetic for induction and maintenance of general anesthesia. After desflurane, it is the volatile anesthetic with the fastest onset and offset.

It is one of the most commonly used volatile anesthetic agents, particularly for outpatient anesthesia, across all ages, as well as in veterinary medicine. Together with desflurane, sevoflurane is replacing isoflurane and halothane in modern anesthesiology. It is often administered in a mixture of nitrous oxide and oxygen.

Sevoflurane \"has an excellent safety record\", but is under review for potential neurotoxicity, especially relevant to administration in infants and children, and rare reports similar to halothane hepatotoxicity. Sevoflurane is the preferred agent for mask induction due to its lesser irritation to mucous membranes.

Sevoflurane was discovered by Ross Terrell and independently by Bernard M Regan. A detailed report of its development and properties appeared in 1975 in a paper authored by Richard Wallin, Bernard Regan, Martha Napoli and Ivan Stern. It was introduced into clinical practice initially in Japan in 1990. The rights for sevoflurane worldwide were held by AbbVie. It is now available as a generic drug.",""



Product Application Notes

Impurity in commercial preparations of Sevoflurane.



Synonyms

1,1,3,3,3-pentafluoro-2-(fluoromethoxy)prop-1-ene ; USP Sevoflurane Related Compound A ; Fluoromethyl 2,2-Difluoro-1-(trifluoromethyl)vinyl Ether



References

Tong, Z. et al.: Chem. Res. Toxicol., 15, 623 (2002); Iyer, R. et al.: J. Pharmacol. Exp. Ther., 283, 1544 (1997);



MSDS



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This page contains information about 1,1,1,3,3-pentafluoro isopropenyl fluoromethyl ether Cas # 58109-34-5 and its Impurities.

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  1. Impurities

  2. 1,1,1,3,3-pentafluoro isopropenyl fluoromethyl ether



Keywords

Keywords: Impurities 1,1,3,3,3-pentafluoro-2-(fluoromethoxy)prop-1-ene ; USP Sevoflurane Related Compound A ; Fluoromethyl 2,2-Difluoro-1-(trifluoromethyl)vinyl Ether CS-O-16090 1,1,1,3,3-pentafluoro isopropenyl fluoromethyl ether Sevoflurane 58109-34-5 180.05 C4H2F6O
Internal standard, Internal standard Sevoflurane, HPLC-MS method validation, HPLC-MS method validation Sevoflurane, LC-MS-MS method validation, LC-MS-MS method validation Sevoflurane, Deuterated internal standard, Deuterated internal standard Sevoflurane, Deuterated Sevoflurane, Deuterium labeled Sevoflurane, Quantitative bioanalytical methods, Quantitative bioanalytical methods Sevoflurane, Blood samples Sevoflurane, Blood concentrations, Heavy drugs, Analysis, Analysis Sevoflurane, Clinical diagnostic, Clinical diagnostic Sevoflurane, Dosing Sevoflurane, Analytical method development, Internal standard method.



Related result for '1,1,1,3,3-pentafluoro isopropenyl fluoromethyl ether'

- Sevoflurane : Impurities

- Sevoflurane : Intermediates



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