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Sacubitrilat D4

Stable Isotopes
CAT No.
:
CS-O-16369

CAS No.

:

1884269-07-1

Molecular Weight

:

387.46

Molecular Formula

:

C22H21D4NO5

Purity

:

>98 %

Inventory Status:

:

Available for Immediate Shipment
 


Useful information

"Sacubitril (/s\u0259\u02c8kju\u02d0b\u1d7btr\u026al/; INN) is an antihypertensive drug used in combination with valsartan. The combination drug valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name Entresto, is a treatment for heart failure. It was approved under the FDA's priority review process for use in heart failure on July 7, 2015.",""



Product Application Notes

Sacubitrilat D4 is the labelled, deuterated version of Sacubitrilatl which is an impurity in the synthesis of Sacubitril, an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.



Synonyms

(2R,4S)-5-{[1,1'-biphenyl]-4-yl}-4-[3-carboxy(2,2,3,3-D4)propanamido]-2-methylpentanoic acid; Desethyl Sacubitril D4



References

McMurray, J., et al.: N. Eng. J. Med., 371 (2014);



MSDS



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Page info:

This page contains information about Sacubitrilat D4 Cas # 1884269-07-1 and its Stable Isotopes.

Sacubitrilat D4 Sacubitrilat D4 Worldwide Suppliers of Sacubitrilat D4 Stable Isotopes Clearsynth 1884269-07-1

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  1. Stable Isotopes

  2. Sacubitrilat D4



Keywords

Keywords: Sacubitrilat D4, CS-O-16369, 1884269-07-1, (2R,4S)-5-{[1,1'-biphenyl]-4-yl}-4-[3-carboxy(2,2,3,3-D4)propanamido]-2-methylpentanoic acid; Desethyl Sacubitril D4, C22H21D4NO5, 387.46, Sacubitrilat D4 is the labelled, deuterated version of Sacubitrilatl which is an impurity in the synthesis of Sacubitril, an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
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Related result for 'Sacubitrilat D4'

- Sacubitril : API Standards

- Sacubitril : Stable Isotopes

- Sacubitril : Metabolites

- Sacubitril : Impurities

- Sacubitril : Intermediates



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