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"Atorvastatin, marketed under the trade name Lipitor among others, is a member of the drug class known as statins, which are used primarily as a lipid-lowering agent and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.
Atorvastatin was first made in August 1985 at Warner-Lambert's Parke-Davis research facility in Ann Arbor, Michigan by a team led by Bruce Roth. From 1996 to 2012 under the trade name Lipitor, atorvastatin became the world's best-selling drug to that point, with more than US$125 billion in sales over approximately 14.5 years. In the UK atorvastatin costs about 2 pounds per month as of 2016.",""
Impurity in commercial preparations of Atorvastatin.
(3S,5R)-Atorvastatin Calcium Salt;Atorvastatin EP Impurity B ;Atorvastatin Related Compound B;(3S,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phehydroxyheptanoate calcium salt;(3S,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phehydroxyheptanoatecacium salt;3S-5R Atorvastatincacium.
Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.:clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmcokinet., 25, 97 (2000),
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This page contains information about Atorvastatin EP Impurity B Cas # 887196-25-0 and its Impurities.
Atorvastatin EP Impurity B Atorvastatin EP Impurity B Worldwide Suppliers of Atorvastatin EP Impurity B https://www.clearsynth.com/en/CSO20027.html Impurities Clearsynth 887196-25-0
Regular price: $800 In stock
Product rating: 9 Atorvastatin EP Impurity B based on 20 ratings
Keywords: Impurities (3S,5R)-Atorvastatin Calcium Salt;Atorvastatin EP Impurity B ;Atorvastatin Related Compound B;(3S,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phehydroxyheptanoate calcium salt;(3S,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phehydroxyheptanoatecacium salt;3S-5R Atorvastatincacium. CS-O-20027 Atorvastatin EP Impurity B Atorvastatin 887196-25-0 1155.34 C66H6CaF2N4O10
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