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Atorvastatin EP Impurity B

Impurities
CAT No.
:
CS-O-20027

CAS No.

:

887196-25-0

Molecular Weight

:

1155.34

Molecular Formula

:

C66H6CaF2N4O10

Purity

:

98.13 %

Long Term Storage

:

2-8° C

Inventory Status:

:

Available for Immediate Shipment

HS Code:

:

29049090

 

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800.00 / 25mg

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Useful information

"Atorvastatin, marketed under the trade name Lipitor among others, is a member of the drug class known as statins, which are used primarily as a lipid-lowering agent and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.

Atorvastatin was first made in August 1985 at Warner-Lambert's Parke-Davis research facility in Ann Arbor, Michigan by a team led by Bruce Roth. From 1996 to 2012 under the trade name Lipitor, atorvastatin became the world's best-selling drug to that point, with more than US$125 billion in sales over approximately 14.5 years. In the UK atorvastatin costs about 2 pounds per month as of 2016.",""



Product Application Notes

Impurity in commercial preparations of Atorvastatin.



Synonyms

(3S,5R)-Atorvastatin Calcium Salt;Atorvastatin EP Impurity B ;Atorvastatin Related Compound B;(3S,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phehydroxyheptanoate calcium salt;(3S,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phehydroxyheptanoatecacium salt;3S-5R Atorvastatincacium.



References

Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993), Heinonen, T.M., et al.:clin. Ther., 18, 853 (1996), Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmcokinet., 25, 97 (2000),



MSDS



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  1. Impurities

  2. Atorvastatin EP Impurity B



Keywords

Keywords: Impurities (3S,5R)-Atorvastatin Calcium Salt;Atorvastatin EP Impurity B ;Atorvastatin Related Compound B;(3S,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phehydroxyheptanoate calcium salt;(3S,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phehydroxyheptanoatecacium salt;3S-5R Atorvastatincacium. CS-O-20027 Atorvastatin EP Impurity B Atorvastatin 887196-25-0 1155.34 C66H6CaF2N4O10
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Related result for 'Atorvastatin EP Impurity B'

- Atorvastatin : API Standards

- Atorvastatin : Stable Isotopes

- Atorvastatin : Metabolites

- Atorvastatin : Impurities

- Atorvastatin : Glucuronides

- Atorvastatin : Intermediates



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