Helpline Tollfree +1.800.650.8239 info@clearsynth.com

OUR QUALITY: ISO 9001:2015 | ISO 14001:2015 | OHSAS 18001:2007 | ISO Guide 34:2009 | ISO/IEC 17025:2005

We speak your language 

(1R,3R)-9H-pyrido[3,4-B]indole-3-carboxylic acid, 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride

Impurities
CAT No.
:
CS-O-20035

CAS No.

:

171752-68-4

Molecular Weight

:

386.82

Molecular Formula

:

C20H1ClN2O4

Purity

:

>98%

Inventory Status:

:

Available for Immediate Shipment

HS Code:

:

29049090

 

Purchase Online

Price 1 ( USD ) :

100.00 / 25mg

X

Units

Price 2 ( USD ) :

150.00 / 50mg

X

Units




Money
Back Guarantee

48 Hours Delivery
(For In-stock compounds)

Online
Purchase Protection


Useful information

"Tadalafil (INN) is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the name Cialis /si\u02c8\u00e6l\u1d7bs/ see-AL-iss, and under the name Adcirca /\u00e6d\u02c8s\u025c\u02d0rk\u0259/ ad-SUR-k\u0259 for the treatment of pulmonary arterial hypertension. In October 2011 the U.S. Food and Drug Administration (FDA) approved Cialis for treating the signs and symptoms of benign prostatic hyperplasia (BPH) as well as a combination of BPH and erectile dysfunction when the conditions coincide. It initially was developed by the biotechnology company ICOS, and then again developed and marketed worldwide by Lilly ICOS, LLC, the joint venture of ICOS Corporation and Eli Lilly and Company. Cialis tablets, in 2.5 mg, 5 mg, 10 mg, and 20 mg doses, are yellow, film-coated, and almond-shaped. The approved dose for pulmonary arterial hypertension is 40 mg (two 20 mg tablets) once daily.

Tadalafil is also manufactured and sold under the name of Tadacip by the Indian pharmaceutical company Cipla in doses of 10 mg and 20 mg.

On November 21, 2003 the FDA approved tadalafil (as Cialis) for sale in the United States as the third ED prescription drug pill (after sildenafil (Viagra) and vardenafil (Levitra)). Like sildenafil and vardenafil, tadalafil is recommended as an 'as needed' medication. Cialis is the only one of the three that is also offered as a once-daily medication.

Moreover, tadalafil was approved in May 2009 in the United States for the treatment of pulmonary arterial hypertension and is under regulatory review in other regions for this condition. In late November 2008, Eli Lilly sold the exclusive rights to commercialize tadalafil for pulmonary arterial hypertension in the United States to United Therapeutics for an upfront payment of $150 million.",""



Product Application Notes

Impurity in commercial preparations of Tadalafil



Synonyms

1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride;(1R,3R)-9H-pyrido[3,4-B]indole-3-carboxylic acid, 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride;(1R,3R)-methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indolechloride



References

Carrier, S., et al.:can. J. Urol., 10(1), 12 (2003), Doggrell, S.A., et al.: Expert Opin. Pharmcother., 6, 75 (2005), Forgue, S.T., et al.: Br. J.clin. Pharmcol., 61, 280 (2005),



MSDS



Have any questions ?

We normally respond within 8 hours.

Subject :

  Stock Status

  Bulk Pricing

  Custom QTY Quote

  Request MSDS

  Request COA

  Other






Page info:

This page contains information about (1R,3R)-9H-pyrido[3,4-B]indole-3-carboxylic acid, 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride Cas # 171752-68-4 and its Impurities.

(1R,3R)-9H-pyrido[3,4-B]indole-3-carboxylic acid, 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride (1R,3R)-9H-pyrido[3,4-B]indole-3-carboxylic acid, 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride Worldwide Suppliers of (1R,3R)-9H-pyrido[3,4-B]indole-3-carboxylic acid, 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride Impurities Clearsynth 171752-68-4

Regular price: $100 In stock

Product rating: 9 (1R,3R)-9H-pyrido[3,4-B]indole-3-carboxylic acid, 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride based on 20 ratings

  1. Impurities

  2. (1R,3R)-9H-pyrido[3,4-B]indole-3-carboxylic acid, 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride



Keywords

Keywords: Impurities 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride;(1R,3R)-9H-pyrido[3,4-B]indole-3-carboxylic acid, 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride;(1R,3R)-methyl 1-(benzo[d][1,3]dioxol-5-yl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indolechloride CS-O-20035 (1R,3R)-9H-pyrido[3,4-B]indole-3-carboxylic acid, 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride Tadalafil 171752-68-4 386.82 C20H1ClN2O4
Internal standard, Internal standard Tadalafil, HPLC-MS method validation, HPLC-MS method validation Tadalafil, LC-MS-MS method validation, LC-MS-MS method validation Tadalafil, Deuterated internal standard, Deuterated internal standard Tadalafil, Deuterated Tadalafil, Deuterium labeled Tadalafil, Quantitative bioanalytical methods, Quantitative bioanalytical methods Tadalafil, Blood samples Tadalafil, Blood concentrations, Heavy drugs, Analysis, Analysis Tadalafil, Clinical diagnostic, Clinical diagnostic Tadalafil, Dosing Tadalafil, Analytical method development, Internal standard method.



Related result for '(1R,3R)-9H-pyrido[3,4-B]indole-3-carboxylic acid, 1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl), methyl ester, hydrochloride'

- Tadalafil : API Standards

- Tadalafil : Stable Isotopes

- Tadalafil : Metabolites

- Tadalafil : Impurities

- Tadalafil : Intermediates



QUICK ENQUIRY

Specific product requirements



Thank you! Your submission has been received!

Oops! Something went wrong while submitting the form :(






NORTH AMERICAN SALES AND R&D CENTRE

CLEARSYNTH CANADA INC.
2395 Speakman Drive,
Lab: 1001, Mississauga, ON,
Canada L5K 1B3
T : +1-289-729-0060

ASIA R&D CENTRE

CLEARSYNTH RESEARCH CENTRE
Plot No. 177, IDA, Mallapur,
Hyderabad- 500076,
Telangana, India.
T : +91-40-27155481

ASIA OFFICE

CLEARSYNTH LABS LTD
17, Lotus Business Park,
Andheri (W), Mumbai - 400053
India
T : +91-22-45045945