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(1S,2R) Bortezomib

Chiral Standards
CAT No.
:
CS-O-20087

CAS No.

:

1132709-16-0

Molecular Weight

:

384.24

Molecular Formula

:

C19H25BN4O4

Purity

:

99.47 %

Long Term Storage

:

2-8°C

Inventory Status:

:

Available for Immediate Shipment
 

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Useful information

"Bortezomib (BAN, INN and USAN; marketed as Velcade by Millennium Pharmaceuticals; Neomib by Getwell and Bortecad by Cadila Healthcare) is an anti-cancer drug and the first therapeutic proteasome inhibitor to be used in humans. Proteasomes are cellular complexes that break down proteins. In some cancers, the proteins that normally kill cancer cells are broken down too quickly. Bortezomib interrupts this process and lets those proteins kill the cancer cells. It is approved in the U.S. and Europe for treating relapsed multiple myeloma and mantle cell lymphoma. In multiple myeloma, complete clinical responses have been obtained in patients with otherwise refractory or rapidly advancing disease.",""



Product Application Notes

(1S,3R)-Bortezomib is an diastereomer of Bortezomib , the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer. A reversible inhibitor of the 26S proteasome-a barrel-shaped multiprotein particle found in the nucleus



Synonyms

(1S,2R) Bortezomib;[(1S)-3-methyl-1-[(2R)-3-phenyl-2-(pyrazin-2-ylformamido)propanamido]butyl]boronc Acid



References

Nawrcki, S.T., et al:cacer Reseach, 65, 11510 (2005); Drahlc.:chem. and Eng. News, 87, 41 (2009)



MSDS



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This page contains information about (1S,2R) Bortezomib Cas # 1132709-16-0 and its Chiral Standards.

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  1. Chiral Standards

  2. (1S,2R) Bortezomib



Keywords

Keywords: Chiral Standards (1S,2R) Bortezomib;[(1S)-3-methyl-1-[(2R)-3-phenyl-2-(pyrazin-2-ylformamido)propanamido]butyl]boronc Acid CS-O-20087 (1S,2R) Bortezomib Bortezomib 1132709-16-0 384.24 C19H25BN4O4



Related result for '(1S,2R) Bortezomib'

- Bortezomib : API Standards

- Bortezomib : Stable Isotopes

- Bortezomib : Metabolites

- Bortezomib : Impurities

- Bortezomib : Chiral Standards

- Bortezomib : Intermediates



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