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"Methotrexate (MTX), formerly known as amethopterin, is a chemotherapy agent and immune system suppressant. It is used to treat cancer, autoimmune diseases, ectopic pregnancy, and for medical abortions. Types of cancers it is used for include breast cancer, leukemia, lung cancer, lymphoma, and osteosarcoma. Types of autoimmune diseases it is used for include psoriasis, rheumatoid arthritis, and Crohn's disease. It can be given by mouth or by injection.
Common side effects include nausea, feeling tired, fever, increased risk of infection, low white blood cell counts, and breakdown of the skin inside the mouth. Other side effects may include liver disease, lung disease, lymphoma, and severe skin rashes. People on long-term treatment should be regularly checked for side effects. It is not safe during breastfeeding. In those with kidney problems, lower doses may be needed. It acts by blocking the body's use of folic acid.
Methotrexate was made in 1947 and initially came into medical use to treat cancer, as it was less toxic than the current treatments. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Methotrexate is available as a generic medication. The wholesale cost as of 2014 in the developing world is between US$0.06 and 0.36 per day for the form taken by mouth. In the United States, a typical month of treatment costs $25 to $50.",""
Amethopterin; Rheumatrex; 59-05-2; Trexall; Abitrexate;
Rossi, S, ed. (2013; Joint Formulary Committee (2013)
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This page contains information about Methotrexate Cas # 59-05-2 and its Amino acid Derivatives.
Methotrexate Methotrexate Worldwide Suppliers of Methotrexate https://www.clearsynth.com/en/CSO30641.html Amino acid Derivatives Clearsynth 59-05-2
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Keywords: Amino acid Derivatives Amethopterin; Rheumatrex; 59-05-2; Trexall; Abitrexate; CS-O-30641 Methotrexate Methotrexate 59-05-2 454.44 C20H22N8O5
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