Search by CAS No , Chemical Name or Molecular Formula
Long Term Storage
"Moxidectin (Milbemycin B) is an anthelmintic drug which kills parasitic worms (helminths), and is used for the prevention and control of heartworm and intestinal worms. It can be found in treatments prescribed for animals such as dogs, cats, horses, cattle and sheep. Application methods for moxidectin vary by treatment, and include oral, topical, and injectable solutions. Cydectin Pour On is a trade name for a formulation for use on cattle and red deer. Moxidectin has shown some successes in the treatment of humans suffering from Onchocerciasis, 'river-blindness', by showing substantial reduction of microfilarial loads, or 'bumps', associated with extreme itching and migration of larvae in the late stage. The switch from Ivermectin use would reduce the chances of the helminth's larvae from developing immunity. However, more studies are required to highlight its ability and its toxicity within the human body at high doses.
Moxidectin is a semisynthetic derivative of nemadectin which is produced by fermentation by Streptomyces cyano-griseus. This Streptomyces species was discovered in a soil sample from Australia in the late 1980s collected by an agronomist working for the American Cyanamid company.
Moxidectin treats and controls some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels. These channels are vital to the function of invertebrate nerve and muscle cells; when moxidectin binds to the channels, it disrupts neurotransmission, resulting in paralysis and death of the parasite.
Studies of moxidectin show the side effects vary by animal and may be affected by the product\u2019s formulation, application method and dosage. The products are usually recommended by a veterinarian to ensure correct use and application. Herding dogs may be avermectin-sensitive, but avermectin-sensitive dogs can tolerate standard doses for heartworm prevention. Moxidectin is apparently safe for collie breeds. As a heartworm preventative, moxidectin can be injected once every six months under the brand name Proheart6, or every 12 months under the brand name Proheart SR 12.",""
(Asato & France 1990);'Study comparing moxidectin and ivermectin in subjects with Onchocerca volvulus infection', retrieved 17 November 2009
We normally respond within 8 hours.
This page contains information about Moxidectin Cas # 113507-06-5 and its Inhibitors.
Moxidectin Moxidectin Worldwide Suppliers of Moxidectin https://www.clearsynth.com/en/CSO30664.html Inhibitors Clearsynth 113507-06-5
Product rating: 9 Moxidectin based on 20 ratings
Keywords: Inhibitors CS-O-30664 Moxidectin Moxidectin 113507-06-5 639.82 C37H53NO8
Specific product requirements
CLEARSYNTH CANADA INC.
2395 Speakman Drive,
Lab: 1001, Mississauga, ON,
Canada L5K 1B3
T : +1-289-729-0060
CLEARSYNTH RESEARCH CENTRE
Plot No. 177, IDA, Mallapur,
T : +91-40-27155481
CLEARSYNTH LABS LTD
17, Lotus Business Park,
Andheri (W), Mumbai - 400053
T : +91-22-45045945