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Nabumetone

Metal Compounds
CAT No.
:
CS-O-30678

CAS No.

:

42924-53-8

Molecular Weight

:

228.29

Molecular Formula

:

C15H16O2

Purity

:

>98%

Appearance

:

White Solid

Inventory Status:

:

Available for Immediate Shipment
 



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Useful information

"Nabumetone is a non-steroidal anti-inflammatory drug (NSAID). Nabumetone has been developed by Beecham. It is available under numerous brand names, such as Relafen, Relifex, and Gambaran.

Nabumetone is a nonacidic NSAID that is rapidly metabolized in the liver to a major active metabolite, 6-methoxy-2-naphthyl acetic acid. As found with previous NSAIDs, nabumetone's active metabolite inhibits the cyclooxygenase enzyme and preferentially blocks COX-2 activity (which is indirectly responsible for the production of inflammation and pain during arthritis). The active metabolite of nabumetone is felt to be the compound primarily responsible for therapeutic effect. Comparatively, the parent drug is a poor inhibitor of COX-2 byproducts, particularly prostaglandins. It may be less nephrotoxic than indomethacin.

Nabumetone has little effect on renal prostaglandin secretion and less of an association with heart failure than other traditional drugs of the class. Effects of nabumetone on blood pressure control in hypertensive patients on ACE inhibitors is also good\u2014equivalent to paracetamol. As of 2015 the cost for a typical month of medication in the United States is 25 to 50 USD.",""



Synonyms

Consolan; Gambaran; Nabugesc 500; Nabumeton; Nabumetone; Nabuser; Relafen; Relifen; Relifex;



References

Gonzalo-Garijo MA, Cordobés-Duran C, Lamilla-Yerga AM, Moreno-Gastón I (2007); Sahu, Prafulla Kumar; Annapurna, M. Mathrusri (2009).



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This page contains information about Nabumetone Cas # 42924-53-8 and its Metal Compounds.

Nabumetone Nabumetone Worldwide Suppliers of Nabumetone Metal Compounds Clearsynth 42924-53-8

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Keywords

Keywords: Metal Compounds Consolan; Gambaran; Nabugesc 500; Nabumeton; Nabumetone; Nabuser; Relafen; Relifen; Relifex; CS-O-30678 Nabumetone Nabumetone 42924-53-8 228.29 C15H16O2



Related result for 'Nabumetone'

- Nabumetone : Stable Isotopes

- Nabumetone : Metabolites

- Nabumetone : Impurities



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