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Ofloxacin

API Standards
CAT No.
:
CS-O-30704

CAS No.

:

82419-36-1

Molecular Weight

:

361.37

Molecular Formula

:

C18H20FN3O4

Purity

:

>98%

Long Term Storage

:

4° C

Inventory Status:

:

Available for Immediate Shipment
 

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Useful information

"Ofloxacin is an antibiotic useful for the treatment of a number of bacterial infections. When taken by mouth or injection into a vein this includes pneumonia, cellulitis, urinary tract infections, prostatitis, plague and certain types of infectious diarrhea. Other uses, along with other medications, include multidrug resistant tuberculosis. An eye drop may be used for a superficial bacterial infection of the eye and an ear drop may be used for otitis media when there is a hole in the ear drum.

When taken by mouth common side effects include vomiting, diarrhea, headache, and rash. Other serious side effect include tendon rupture, numbness due to nerve damage, seizures, and psychosis. Use in pregnancy is typically not recommended. Ofloxacin is in the fluoroquinolone family of medications. It works by interfering with the bacteria's DNA.

Ofloxacin was patented in 1980 and approved for medical use in 1985. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Ofloxacin is available as a generic medication. The wholesale cost in the developing world is about 3.27 USD per month. In the United States a course of treatment costs about 50 to 100 USD.",""



Product Application Notes

Ofloxacin is a synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.



References

Vrenken, T., et al.: J. Hepatol., 49, 799 (2008), Mazzcco, G., et al.:clin. Nephrol., 70, 163 (2008), Davies, M., et al.: J. Med.chem., 52, 2683 (2009),



MSDS



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Keywords

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