Montelukast Sulphoxide

Product Name Montelukast Sulphoxide
Alternate Names Montelukast Impurities, Impurities of Montelukast
CAT No. CS-AB-00066
CAS No. 1152185-58-4
Category Impurities
Stock IN-Stock
Mol. Wt. 602.18 g/mol
Mol. For. C₃₅H₃₆ClNO₄S
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Montelukast
Canonical Smiles CC(C)(C1=CC=CC=C1CCC(C2=CC=CC(=C2)C=CC3=NC4=C(C=CC(=C4)Cl)C=C3)S(=O)CC5(CC5)CC(=O)O)O
InchIKey QFTNWCBEAVHLQA-XNHCCDLUSA-N
Inchl InChI=1S/C35H36ClNO4S/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(42(41)23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39)/b15-10+/t32-,42?/m1/s1
IUPAC 2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfinylmethyl]cyclopropyl]acetic acid
Controlled No
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Montelukast Sulphoxide, also known as Montelukast S-oxide or MK-476, is a metabolite of Montelukast, a medication used to treat asthma and allergic rhinitis. Montelukast Sulphoxide is formed in the liver by the oxidation of Montelukast and has been found to have similar pharmacological properties as its parent drug. The usage of Montelukast Sulphoxide has been studied for its potential therapeutic effects in the treatment of various inflammatory diseases, including asthma, allergic rhinitis, and chronic obstructive pulmonary disease (COPD). Research has shown that Montelukast Sulphoxide has anti-inflammatory properties that can reduce airway inflammation and improve lung function in patients with asthma and COPD. Chemically, Montelukast Sulphoxide is a chiral molecule, meaning that it exists in two mirror-image forms. The biological activity of each form can differ, which is why it is important to use the correct enantiomer for therapeutic purposes. Montelukast Sulphoxide is primarily eliminated from the body through the urine and feces, and its half-life ranges from 4 to 7 hours. In conclusion, Montelukast Sulphoxide has shown potential as a therapeutic agent for the treatment of inflammatory diseases, particularly in the respiratory system. Further research is needed to fully understand its pharmacological properties and potential clinical applications.

Related Compounds

Montelukast methanesulfonate IMPURITY | Montelukast EP impurity E | Montelukast Chloroalcohol impurity | Montelukast sodium racemate | Montelukast EP Impurity D+E (Michael Adduct 1+2) | Montelukast Dehydro Impurity | Montelukast Acid impurity | Montelukast Bis-sulfide | Montelukast EP Impurity B | Montelukast EP impurity D | Montelukast EP Impurity C (Mixture of isomers) | Dihydro Montelukast Sodium Salt | Montelukast EP impurity G | Montelukast Dicarboxylic Acid | Cyclopropane-1,1- diylbis(methylene) dimethanesulfonate | Montelukast Diol | ent-Montelukast Sodium Salt | Montelukast EP impurity A | Montelukast EP impurity H | Montelukast Ketocarbinol Impurity | Dihydro Montelukast Sodium Salt | Montelukast sulfone N-Oxide | Montelukast EP impurity F | Montelukast Cyclopropaneacetonitrile | Montelukast 3-Oxo Propanol Impurity | Montelukast Gem-dimethylmethylene Analogue | Montelukast cyclopropaneacetamide (Impurity) | Montelukast Methyl Ester | Montelukast EP Impurity C (R isomer) | Montelukast Cyclizate Ether impurity | Montelukast (3R)-Hydroxy Propanol | Montelukast Sulfone | Des[3-[[(1-Carboxymethyl)cyclopropyl]methyl]thio]-2-propenyl Montelukast Mesylate | Montelukast EP impurity I |

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