Tofacitinib impurity L

Product Name Tofacitinib impurity L
CAT No. CS-AQ-00041
CAS No. 1675248-19-7
Category Impurities
Stock IN-Stock
Mol. Wt. 330.38 g/mol
Mol. For. C₁₆H₂₂N₅O₂
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Therapeutic Anti-Cancer / Oncology
Canonical Smiles CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC(=O)N
InchIKey CRDMXSMPTHMXRD-PWSUYJOCSA-N
Inchl InChI=1S/C16H22N6O2/c1-10-4-6-22(14(24)7-13(17)23)8-12(10)21(2)16-11-3-5-18-15(11)19-9-20-16/h3,5,9-10,12H,4,6-8H2,1-2H3,(H2,17,23)(H,18,19,20)/t10-,12+/m1/s1
IUPAC 3-[(3R,4R)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanamide
Controlled No
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Tofacitinib impurity L is a chemical substance that is used in the pharmaceutical industry as a reference standard for the analysis of Tofacitinib. Tofacitinib is a medication that is used to treat rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It works by inhibiting the activity of a group of enzymes called Janus kinases (JAKs), which play a crucial role in the immune system. Tofacitinib impurity L is a synthetic organic compound that has a molecular formula of C19H19N5O2S. It is classified as an impurity because it is a byproduct of the synthesis of Tofacitinib. It is important to control the presence of impurities in pharmaceutical products because they can affect the safety and efficacy of the medication. In the case of Tofacitinib, impurities can interfere with the binding of the drug to JAKs, reducing its effectiveness. Chemically, Tofacitinib impurity L is a pyridine derivative that contains a sulfonamide group. It has a molecular weight of 381.45 g/mol and a melting point of 220-223°C. Tofacitinib impurity L is soluble in organic solvents such as methanol, ethanol, and acetonitrile. Its chemical structure is determined by various analytical techniques such as nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry. In conclusion, Tofacitinib impurity L is an important reference standard used in the analysis of Tofacitinib. Its chemical information is crucial for the quality control of Tofacitinib and ensuring the safety and efficacy of the medication.

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