Apixaban impurity B

Product Name Apixaban impurity B
Alternate Names Apixaban Impurities, Impurities of Apixaban
CAT No. CS-AQ-00215
CAS No. 1686149-74-5
Category Impurities
Stock IN-Stock
Mol. Wt. 473.52 g/mol
Mol. For. C₂₆H₂₇N₅O₄
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Apixaban
Therapeutic Anti-Thrombotics
Smileys CC1CCC(=O)N(C1)C2=CC=C(C=C2)N3CCC4=C(C3=O)N(N=C4C(=O)N)C5=CC=C(C=C5)OC
Canonical Smiles CC1CCC(=O)N(C1)C2=CC=C(C=C2)N3CCC4=C(C3=O)N(N=C4C(=O)N)C5=CC=C(C=C5)OC
InchIKey NNYVHGAEKIMTND-UHFFFAOYSA-N
Inchl InChI=1S/C26H27N5O4/c1-16-3-12-22(32)30(15-16)18-6-4-17(5-7-18)29-14-13-21-23(25(27)33)28-31(24(21)26(29)34)19-8-10-20(35-2)11-9-19/h4-11,16H,3,12-15H2,1-2H3,(H2,27,33)
IUPAC 1-(4-methoxyphenyl)-6-[4-(5-methyl-2-oxopiperidin-1-yl)phenyl]-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide
Controlled No
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Apixaban impurity B is a chemical compound that is commonly used in the pharmaceutical industry as a reference standard for identifying and quantifying the impurities present in the drug molecule Apixaban. This impurity is generally considered to be an unwanted by-product of the Apixaban synthesis process, and its levels must be kept below a certain threshold to ensure the safety and efficacy of the drug. Chemically, Apixaban impurity B is a low molecular weight organic compound that is characterized by its high solubility in organic solvents like methanol, ethanol, and acetonitrile. Its chemical structure is closely related to that of Apixaban, and it is believed to be a derivative of the drug molecule that has undergone some form of chemical modification during the manufacturing process. In terms of usage, Apixaban impurity B is typically used in the laboratory as a reference standard for analytical testing, particularly in methods like high-performance liquid chromatography (HPLC) and mass spectrometry (MS). By comparing the levels of this impurity in Apixaban drug samples to known standards, researchers can identify and quantify any impurities present in the drug, thereby ensuring the quality and safety of the medication.

Related Compounds

Apixaban Impurity 24 | Apixaban Methyl ester Impurity | Desmethoxy Apixaban | Apixaban Isopropyl Ester Impurity | Apixaban Impurity 29 | Apixaban methyl ester Dimer imp | Apixaban Impurity 32 | O-Desmethyl Apixaban Sulfate | Methyl 5-((4-(3-Carbamoyl-1-(4-methoxyphenyl)-7-oxo-4,5-dihydro-1H-pyrazolo[3,4-c]pyridin-6(7H)-yl)phenyl)amino)pentanoate | Apixaban Amino Acid Impurity | Apixaban Impurity 40 | Apixaban Hydroxy acid Impurity | Apixaban Impurity 17 | Apixaban PG Ester-I | Apixaban Related Compound 5 | Apixaban Impurity 28 | Apixaban Impurity 12 | Apixaban Impurity 3 | Apixaban Impurity 26 | Apixaban Impurity 5 | Apixaban Related Compound 1 | O-Desmethyl Apixaban | Apixaban Impurity 3 | Apixaban Impurity 33 | Apixaban Nitrosoamide impurity | Apixaban Impurity - (3/2 H2O) | Apixaban Chloro Impurity | Apixaban PG Ester-II | Apixaban diacid impurity | Ethyl-2-chloro-2-(2-(4-hydroxy phenyl)hydrazono)acetate | ethyl (Z)-2-chloro-2-(2-(4-methoxyphenyl)hydrazineylidene)acetate | Apixaban impurity D | Apixaban Impurity 51 | Apixaban Impurity 38 | Apixaban Impurity 34 | Ethyl (2E)-2-chloro-2-[2-(4-methoxyphenyl)hydrazinylidene]acetate | Apixaban impurity A | Apixaban Impurity 27 | Apixaban Amino Acid Impurity Hydrochloride | N-Nitroso Apixaban Amino Acid Impurity | Apixaban Impurity 14 | Apixaban Impurity 52 | Ethyl 2-chloro-2-[2-(2-methoxyphenyl)hydrazin-1-ylidene]acetate | Hydroxy O-Demethyl Apixaban | Apixaban Impurity - (2 H2O) | Apixaban carboxybutylaminophenyl | Apixaban impurity E | Apixaban Ethoxy Diethylamide impurity | Apixaban Impurity 44 | Apixaban dimer impurity | Apixaban Related Compound G | Apixaban imp Dimer-2 | Apixaban Impurity 13 Potassium Salt | Apixaban Impurity 43 | Apixaban Impurity 84 | N-Nitroso 5-Chloropentanamide Apixaban | Apixaban Ester Impurity | Apixaban Impurity 16 | Apixaban Impurity 39 | N-(4-methoxyphenyl)nitrous hydrazide | Apixaban Related Compound H | Apixaban Related Compound D | AXN-III | Apixaban Nitrosoacid impurity | Apixaban Impurity C |

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