(Des-Pro-NHEt9)-Leuprolide
| Product Name | (Des-Pro-NHEt9)-Leuprolide |
|---|---|
| CAT No. | CS-AX-01296 |
| CAS No. | 112642-14-5 |
| Category | Impurities |
| Stock | IN-Stock |
| Mol. Wt. | 1085.21 g/mol |
| Mol. For. | C₅₂H₇₂N₁₄O₁₂ |
| Hazardous | This is a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Purity | Not less than 95 % |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | O=C(O)C(CCC/N=C(N)\N)NC(C(CC(C)C)NC(C(CC(C)C)NC(C(CC1=CC=C(O)C=C1)NC(C(CO)NC(C(CC2=CNC3=C2C=CC=C3)NC(C(CC4=CN=CN4)NC(C(CC5)NC5=O)=O)=O)=O)=O)=O)=O)=O |
| Canonical Smiles | CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C(=O)O)NC(=O)C(CC1=CC=C(C=C1)O)NC(=O)C(CO)NC(=O)C(CC2=CNC3=CC=CC=C32)NC(=O)C(CC4=CN=CN4)NC(=O)C5CCC(=O)N5.C(=O)(C(F)(F)F)O |
| InchIKey | LZLMAVOVSHAXJB-ILUHNKAZSA-N |
| Inchl | InChI=1S/C52H72N14O12.C2HF3O2/c1-27(2)18-37(45(71)60-36(51(77)78)10-7-17-56-52(53)54)61-46(72)38(19-28(3)4)62-47(73)39(20-29-11-13-32(68)14-12-29)63-50(76)42(25-67)66-48(74)40(21-30-23-57-34-9-6-5-8-33(30)34)64-49(75)41(22-31-24-55-26-58-31)65-44(70)35-15-16-43(69)59-35;3-2(4,5)1(6)7/h5-6,8-9,11-14,23-24,26-28,35-42,57,67-68H,7,10,15-22,25H2,1-4H3,(H,55,58)(H,59,69)(H,60,71)(H,61,72)(H,62,73)(H,63,76)(H,64,75)(H,65,70)(H,66,74)(H,77,78)(H4,53,54,56);(H,6,7)/t35-,36-,37-,38+,39-,40-,41-,42-;/m0./s1 |
| IUPAC | (2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-3-hydroxy-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylpentanoyl]amino]-4-methylpentanoyl]amino]pentanoic acid;2,2,2-trifluoroacetic acid |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
(Des-Pro-NHEt9)-Leuprolide is a synthetic analog of gonadotropin-releasing hormone (GnRH). It is commonly used in the treatment of prostate cancer, endometriosis, and precocious puberty. The drug works by suppressing the production of testosterone in males and estrogen in females, which can help to slow the growth of cancer cells or alleviate symptoms associated with hormone-dependent conditions.
Chemically, (Des-Pro-NHEt9)-Leuprolide is a peptide composed of 10 amino acids. The drug is administered via injection, either subcutaneously or intramuscularly, and has a half-life of approximately three hours. This short duration of action necessitates frequent dosing, typically every one to three months, depending on the patient's condition.
The drug is generally well-tolerated, but common side effects include hot flashes, fatigue, and headaches. In rare cases, more serious side effects such as anaphylaxis, osteoporosis, and depression may occur.
Overall, (Des-Pro-NHEt9)-Leuprolide is an important treatment option for individuals with hormone-dependent conditions such as prostate cancer, endometriosis, and precocious puberty. Its ability to suppress the production of hormones makes it an effective therapy for managing symptoms and slowing the progression of certain diseases. However, as with any medication, patients should discuss the risks and benefits of treatment with their healthcare provider before starting therapy.
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