([13C6]Leu15)-pTH (human) (H-7234.1000)

([13C6]Leu15)-pTH (human) (H-7234.1000) is a peptide hormone used in research and clinical settings to study the regulation and metabolism of calcium and phosphate in the body. This peptide hormone is a modified version of the parathyroid hormone (PTH), with the addition of six carbon-13 isotopes to the leucine amino acid at position 15. This modification allows for the peptide to be easily distinguished from endogenous PTH in experiments using mass spectrometry or nuclear magnetic resonance imaging. The primary function of PTH is to regulate calcium levels in the body. It does this by stimulating the release of calcium from bone, increasing calcium absorption in the intestines, and decreasing calcium excretion in the kidneys. This hormone also plays a role in the regulation of phosphate levels in the body. The modified version of PTH, ([13C6]Leu15)-pTH (human), allows for more precise measurements of PTH activity and metabolism in the body. ([13C6]Leu15)-pTH (human) can be used in a variety of research applications, including studying the effects of various drugs or conditions on PTH metabolism and activity. It can also be used in clinical settings to diagnose and monitor disorders of calcium and phosphate metabolism, such as hyperparathyroidism or hypoparathyroidism. Overall, the peptide hormone ([13C6]Leu15)-pTH (human) is a valuable tool for researchers and clinicians studying the regulation of calcium and phosphate in the body.