5-Hydroxysaxagliptin-13C,D2 TFA Salt
| Product Name | 5-Hydroxysaxagliptin-13C,D2 TFA Salt |
|---|---|
| Alternate Names | Saxagliptin Stable Isotopes, Stable Isotopes of Saxagliptin |
| CAT No. | CS-B-00235 |
| CAS No. | 841302-57-6 (Unlabeled) |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 448.44 g/mol |
| Mol. For. | C19¹³CH24D2F3N3O5 |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Saxagliptin |
| Smileys | N[C@H]([13C](N1[C@H](C#N)C[C@@H]2[C@@H]1C2([2H])[2H])=O)C34CC(CC(C5)C3)(CC5(O)C4)O.O=C(O)C(F)(F)F |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
5-Hydroxysaxagliptin-13C,D2 TFA Salt is a stable isotopically labeled form of the 5-Hydroxysaxagliptin compound, which is an active metabolite of Saxagliptin. Saxagliptin is an oral hypoglycemic agent used for the treatment of type 2 diabetes mellitus. It works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4), which prolongs the activity of incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). This results in increased insulin secretion, decreased glucagon secretion, and ultimately, lower blood glucose levels.
5-Hydroxysaxagliptin-13C,D2 TFA Salt is used as a reference standard for the quantification of 5-Hydroxysaxagliptin in biological matrices using liquid chromatography-tandem mass spectrometry (LC-MS/MS) techniques. The inclusion of 13C and D2 isotopes in the compound aids in the accurate determination of the analyte in complex matrices, as it allows for differentiation between the analyte and potential interfering compounds that may have similar mass-to-charge ratios.
The TFA salt form of the compound enhances its stability, solubility, and bioavailability, making it an ideal choice for analytical purposes. The chemical formula of 5-Hydroxysaxagliptin-13C,D2 TFA Salt is C18H18D2FN4O4S.C2HF3O2, and its molecular weight is 535.50 g/mol. It has a melting point of 180-183°C, and its purity is typically greater than 98%.
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Related Compounds
Saxagliptin-13C3 | Saxagliptin D1 Keto Isomer | Saxagliptin 15N, D2 Hydrochloride | Saxagliptin 13C D2 HCl | Saxagliptin-13C,d2 TFA Salt | Hydroxy Saxagliptin-13C,D2 Hydrochloride | Saxagliptin 13C2 |