Acenocoumarol-d5

Product Name Acenocoumarol-d5
Alternate Names Acenocoumarol Stable Isotopes, Stable Isotopes of Acenocoumarol
CAT No. CS-BR-00001
CAS No. 152-72-7(Unlabeled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Acenocoumarol
Smileys CC(CC(C(C([2H])=C1[2H])=C(C([2H])=C1[N](=O)=O)[2H])([2H])C(C2=O)=C(C3=CC=CC=C3O2)O)=O
Controlled No
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Acenocoumarol-d5 is a deuterated form of acenocoumarol, which is a coumarin derivative used as an oral anticoagulant medication. It is primarily prescribed for the prevention and treatment of thromboembolic disorders, including deep vein thrombosis, pulmonary embolism, and stroke. Acenocoumarol-d5 works by inhibiting the vitamin K-dependent clotting factors in the liver, thus preventing the formation of blood clots. Chemically, acenocoumarol-d5 is a racemic mixture of two enantiomers, S-(+)-acenocoumarol and R-(-)-acenocoumarol, both of which are deuterated at the 5-position of the coumarin ring. The deuterium labeling is used for pharmacokinetic studies, as it allows for the differentiation of the labeled drug from the endogenous compound and provides more accurate measurements of drug concentrations in biological samples. Acenocoumarol-d5 is typically administered orally in tablet form and is metabolized in the liver by cytochrome P450 enzymes. The drug has a long half-life of approximately 8-11 hours and requires careful monitoring of blood clotting parameters to ensure therapeutic efficacy and avoid bleeding complications. Overall, acenocoumarol-d5 is an important medication for the prevention and treatment of thromboembolic disorders, and its deuterium labeling provides valuable insights into its pharmacokinetics and metabolism.

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