5'-Deoxy-5-fluorouridine-D3
| Product Name | 5'-Deoxy-5-fluorouridine-D3 |
|---|---|
| Alternate Names | Uridine Stable Isotopes, Stable Isotopes of Uridine |
| CAT No. | CS-BU-00100 |
| CAS No. | 3094-09-5(unlabeled) |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | Not Available |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Uridine |
| Therapeutic | Anti-Cancer / Oncology |
| Smileys | O[C@H]1[C@H](N(C=C(F)C2=O)C(N2)=O)O[C@@](C([2H])[2H])([2H])[C@H]1O |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
5'-Deoxy-5-fluorouridine-D3 is a nucleoside analogue that has found applications in the field of cancer therapy. It is a deuterium-labeled derivative of the chemotherapeutic agent 5'-Deoxy-5-fluorouridine (5-FU), which is widely used in the treatment of gastrointestinal and breast cancers.
5'-Deoxy-5-fluorouridine-D3 has the same mechanism of action as 5-FU, which is to inhibit the enzyme thymidylate synthase, thereby preventing the synthesis of DNA. This leads to the disruption of the cancer cell's ability to divide and replicate, ultimately resulting in cell death.
In addition to its use in cancer therapy, 5'-Deoxy-5-fluorouridine-D3 is also used as a tracer in metabolic studies. Its deuterium labeling allows for tracking of its metabolic fate in the body, providing insights into its pharmacokinetics and pharmacodynamics.
In terms of chemical information, 5'-Deoxy-5-fluorouridine-D3 has a molecular formula of C9H9D3FN2O5 and a molecular weight of 256.23 g/mol. It is typically administered intravenously and has a half-life of approximately 10-20 minutes.
Overall, 5'-Deoxy-5-fluorouridine-D3 is a valuable tool in cancer therapy and metabolic studies, offering insights into the mechanisms of cancer cell growth and the fate of drugs in the body.
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Related Compounds
Trifluridine 13C15N2 | Uridine-5,6-d2 | Ara-uridine-5'-monophosphate disodium salt 13C,15N2 | Uridine-3’,5’-cyclic-13C5 Monophosphate Sodium Salt | Uridine-2 13C-1,3 15N2 | Uridine 5'-Diphospho-a-D-glucose 13C6 Diammonium Salt | Uridine-[5',5'-D2] | Ara-uridine 13C5 | Tetrahydro uridine D3 |