7a-Methylthiol spironolactone-D5

Product Name 7a-Methylthiol spironolactone-D5
Alternate Names Spironolactone Stable Isotopes, Stable Isotopes of Spironolactone
CAT No. CS-BU-00105
CAS No. 38753-77-4(Unlabeled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Spironolactone
Smileys C[C@@]12[C@](OC3=O)(CC3([2H])[2H])CC[C@@]1([H])[C@@]([C@@H](CC4=C([2H])C5=O)SC)([H])[C@]([C@]4(CC5([2H])[2H])C)([H])CC2
Canonical Smiles CC12CCC(=O)C=C1CC(C3C2CCC4(C3CCC45CCC(=O)O5)C)SC
InchIKey FWRDLPQBEOKIRE-RJKHXGPOSA-N
Inchl InChI=1S/C23H32O3S/c1-21-8-4-15(24)12-14(21)13-18(27-3)20-16(21)5-9-22(2)17(20)6-10-23(22)11-7-19(25)26-23/h12,16-18,20H,4-11,13H2,1-3H3/t16-,17-,18+,20+,21-,22-,23+/m0/s1
IUPAC (7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-7-methylsulfanylspiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione
Controlled No
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7a-Methylthiol spironolactone-D5 is a deuterated analogue of spironolactone, a medication used primarily to treat high blood pressure, heart failure, and edema caused by various medical conditions. The addition of deuterium in the molecule of 7a-Methylthiol spironolactone-D5 allows for better detection and quantification of the drug in biological samples. The chemical formula of 7a-Methylthiol spironolactone-D5 is C24H27D5O4S, and its molecular weight is 433.64 g/mol. The drug’s unique chemical structure consists of a 7a-methylthio substituent, a five-membered lactone ring, and a tetrahydronaphthalene ring system. 7a-Methylthiol spironolactone-D5 works by blocking the action of aldosterone, a hormone that regulates salt and water balance in the body. This results in increased excretion of sodium and water, leading to a decrease in blood pressure and fluid retention. The drug is typically administered orally, and its effects can be seen within a few hours of ingestion. While 7a-Methylthiol spironolactone-D5 has been used in clinical studies to assess spironolactone metabolism and pharmacokinetics, it is not currently approved for clinical use. As with any medication, it is important to consult with a healthcare professional before taking 7a-Methylthiol spironolactone-D5 or any other drug.

Related Compounds

Spironolactone D7 (Major) | Spironolactone D3 | Spironolactone-d4 | Spironolactone D6 |

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