Tetrahydrocortisone-2,2,3,4,4-D5

Product Name Tetrahydrocortisone-2,2,3,4,4-D5
Alternate Names Hydrocortisone Stable Isotopes, Stable Isotopes of Hydrocortisone
CAT No. CS-BX-00374
CAS No. 1485501-48-1
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Hydrocortisone
Smileys C[C@]([C@@]1(O)C(CO)=O)(C2)[C@](CC1)([H])[C@@](CC[C@@]3([H])[C@@]4(CC([2H])([2H])[C@](O)([2H])C3([2H])[2H])C)([H])[C@]4([H])C2=O
Canonical Smiles CC12CCC(CC1CCC3C2C(=O)CC4(C3CCC4(C(=O)CO)O)C)O
InchIKey SYGWGHVTLUBCEM-VFFMWAQASA-N
Inchl InChI=1S/C21H32O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-15,18,22-23,26H,3-11H2,1-2H3/t12-,13-,14+,15+,18-,19+,20+,21+/m1/s1/i10D2,11D2,18D
IUPAC (3R,5R,8S,9S,10S,13S,14S,17R)-9,12,12-trideuterio-17-(2,2-dideuterio-2-hydroxyacetyl)-3,17-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-11-one
Controlled No
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Tetrahydrocortisone-2,2,3,4,4-D5 is a stable isotope labeled analog of the naturally occurring hormone cortisol. It is primarily used in research and clinical settings to study the metabolic pathways and mechanisms of cortisol in the body. Cortisol is a steroid hormone that plays a crucial role in regulating various physiological processes, including metabolism, immune response, and stress response. It is produced in the adrenal gland and released into the bloodstream in response to stress or low blood sugar levels. Cortisol levels can also be affected by various factors such as diet, exercise, and medication. Tetrahydrocortisone-2,2,3,4,4-D5 is used as a tracer molecule in studies that aim to understand the metabolism and excretion of cortisol in the body. This is achieved by administering a small amount of the labeled compound to a subject and tracking its movement and transformation through various metabolic pathways. The chemical structure of Tetrahydrocortisone-2,2,3,4,4-D5 is similar to that of cortisol, with the addition of five deuterium atoms. Deuterium is a stable isotope of hydrogen that does not affect the biological activity of the compound. However, its presence allows for precise tracking and measurement of the compound in biological samples. In conclusion, Tetrahydrocortisone-2,2,3,4,4-D5 is a valuable tool in the study of cortisol metabolism and related physiological processes. Its use in research and clinical settings has contributed significantly to our understanding of the role of cortisol in health and disease.

Related Compounds

Allotetrahydrocortisone-[d5] | Allotetrahydrocortisone-[d5] (Solution) | Allotetrahydrocortisone-[D4] | Hydrocortisone D4 | Cortisol-[d4] |

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