5,6-Dihydrothymine D6

Product Name 5,6-Dihydrothymine D6
CAT No. CS-C-00376
CAS No. 334473-42-6
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Smileys CC1CNC(=O)NC1=O
Canonical Smiles CC1CNC(=O)NC1=O
InchIKey NBAKTGXDIBVZOO-LIDOUZCJSA-N
Inchl InChI=1S/C5H8N2O2/c1-3-2-6-5(9)7-4(3)8/h3H,2H2,1H3,(H2,6,7,8,9)/i1D3,2D2,3D
IUPAC 5,6,6-trideuterio-5-(trideuteriomethyl)-1,3-diazinane-2,4-dione
Controlled No
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5,6-Dihydrothymine D6 is a deuterated form of 5,6-dihydrothymine, a nitrogenous base found in DNA and RNA. It is used primarily in research as a stable isotope-labeled internal standard for the quantification of 5,6-dihydrothymine in biological samples. The chemical formula of 5,6-Dihydrothymine D6 is C5H6D6N2O2, and its molecular weight is 160.18 g/mol. It is a white to off-white crystalline powder that is soluble in water and organic solvents such as methanol, ethanol, and acetonitrile. 5,6-Dihydrothymine D6 is synthesized by deuterating the precursor molecule, 5,6-dihydrouracil, using deuterated reagents. The resulting product is then converted to 5,6-dihydrothymine D6 via a multi-step chemical reaction. The stable isotope-labeled 5,6-dihydrothymine D6 is used as an internal standard in mass spectrometry-based methods for the quantification of 5,6-dihydrothymine in biological samples such as urine and plasma. This is important in studies investigating the role of 5,6-dihydrothymine in DNA damage and repair, as well as in cancer research. Overall, 5,6-Dihydrothymine D6 is an important tool in the field of molecular biology and biochemistry, allowing for accurate and precise quantification of this important nitrogenous base in biological samples.

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