(+/-)-Promethazine-d4 HCl (phenothiazine-1,3,7,9-d4)
| Product Name | (+/-)-Promethazine-d4 HCl (phenothiazine-1,3,7,9-d4) |
|---|---|
| Alternate Names | Promethazine Stable Isotopes, Stable Isotopes of Promethazine |
| CAT No. | CS-C-00530 |
| CAS No. | 1173018-74-0 |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 324.9 g/mol |
| Mol. For. | Not Available |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Promethazine |
| Smileys | [H]Cl.[2H]C1=CC([2H])=CC2=C1N(C3=C(S2)C=C([2H])C=C3[2H])CC(C)N(C)C |
| Canonical Smiles | CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.Cl |
| InchIKey | XXPDBLUZJRXNNZ-RPMJCVFWSA-N |
| Inchl | InChI=1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H/i6D,7D,8D,9D; |
| IUPAC | N,N-dimethyl-1-(1,3,7,9-tetradeuteriophenothiazin-10-yl)propan-2-amine;hydrochloride |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
(+/-)-Promethazine-d4 HCl (phenothiazine-1,3,7,9-d4) is a deuterated form of promethazine hydrochloride, which is a medication used to treat various conditions such as allergies, nausea, and vomiting. This compound is a phenothiazine derivative that acts as an antihistamine, antiemetic, and sedative. The deuterium substitution in this compound makes it useful in pharmacokinetic studies to monitor the metabolism and pharmacodynamics of promethazine in vivo.
The chemical formula of (+/-)-Promethazine-d4 HCl is C17H14D4ClN3S, and its molecular weight is 329.87 g/mol. The compound is a white to off-white powder that is soluble in water. It is typically administered orally or intravenously, although it can also be given as a rectal suppository.
The mechanism of action of promethazine is not fully understood, but it is believed to block histamine receptors in the brain and periphery, as well as dopamine receptors in the chemoreceptor trigger zone. This results in a reduction in allergic symptoms, nausea, and vomiting, as well as sedation and relaxation.
Overall, (+/-)-Promethazine-d4 HCl is an important tool in pharmacological research for understanding the effectiveness and safety of promethazine in treating various conditions. Its deuterium substitution allows for more precise measurements and understanding of the drug's pharmacokinetics and pharmacodynamics.
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Related Compounds
Promethazine D6 hydrochloride | rac N-Demethyl Promethazine-d3 Hydrochloride | Promethazine Sulfoxide-d6 | Iso Promethazine-d3 Hydrochloride |