2'-Deoxyuridine-5,6-d2

2?-Deoxyuridine-5,6-d2 is a modified form of 2?-deoxyuridine, a nucleoside commonly found in DNA. The compound is labeled with deuterium atoms at the 5th and 6th positions, which makes it useful in various research applications. The deuterium labeling provides a distinct marker for tracking metabolic pathways and understanding biochemical reactions involving DNA synthesis. One of the primary uses of 2?-Deoxyuridine-5,6-d2 is in the study of DNA replication and repair mechanisms. Researchers often use it as a tracer to follow the incorporation of nucleosides into DNA strands. The labeled compound can also be used to investigate the effects of drugs or other compounds on DNA replication and repair processes. Chemically, 2?-Deoxyuridine-5,6-d2 is a white crystalline powder that is soluble in water and other polar solvents. Its molecular formula is C9H10D2N2O5, and it has a molecular weight of 238.24 g/mol. The compound is stable under normal laboratory conditions but should be handled with care as it can be hazardous if ingested or inhaled. In summary, 2?-Deoxyuridine-5,6-d2 is a valuable tool for investigating DNA replication and repair mechanisms. Its deuterium labeling provides a unique marker for tracking metabolic pathways and understanding biochemical reactions involving DNA synthesis. Researchers can use this compound to study the effects of drugs or other compounds on DNA replication and repair processes.