7beta-Hydroxycholesterol-25,26,26,26,27,27,27 D7

7?-Hydroxycholesterol-25,26,26,26,27,27,27-d7 is a deuterated derivative of the naturally occurring cholesterol metabolite, 7?-hydroxycholesterol. This compound has been labeled with seven deuterium atoms at the terminal end of the molecule, making it useful in a variety of research applications. One of the primary uses of 7?-Hydroxycholesterol-25,26,26,26,27,27,27-d7 is as an internal standard in mass spectrometry-based assays. This is due to the fact that its deuterated structure allows for precise quantification of analytes in complex biological matrices. Additionally, it is often used as a reference compound for studying the metabolism of cholesterol and other sterols in vivo. From a chemical perspective, 7?-Hydroxycholesterol-25,26,26,26,27,27,27-d7 is a hydroxylated derivative of cholesterol that is produced by the activity of the enzyme cholesterol 7?-hydroxylase. This reaction occurs primarily in the liver and is a critical step in the biosynthesis of bile acids. Additionally, 7?-hydroxycholesterol has been shown to act as an endogenous activator of the liver X receptor, which plays a key role in cholesterol homeostasis. Overall, 7?-Hydroxycholesterol-25,26,26,26,27,27,27-d7 is a valuable tool for researchers studying cholesterol metabolism, bile acid synthesis, and related pathways. Its precise quantification capabilities and ability to act as an internal standard make it an important reference compound in many fields.