3beta-Allopregnanolone D4

5?-Pregnan-3?-ol-20-one-17?,21,21,21-d4, also known as Allopregnanolone-d4, is a synthetic isotope-labeled steroid hormone. It is a deuterated form of Allopregnanolone, which is a naturally occurring steroid hormone that is produced in the human body. Allopregnanolone-d4 is widely used in scientific research as a stable isotope-labeled internal standard for the quantification and detection of Allopregnanolone in biological samples. It is commonly used in pharmacokinetic studies to determine the absorption, distribution, metabolism, and excretion of Allopregnanolone in the body. Additionally, it is used in toxicology studies to investigate the effects of Allopregnanolone on the body. Chemically, Allopregnanolone-d4 is a C21 steroid hormone that is synthesized from progesterone. It acts as a potent positive allosteric modulator of GABA-A receptors, which are ionotropic receptors that mediate the inhibitory effects of the neurotransmitter GABA in the central nervous system. Allopregnanolone-d4 has been shown to have anxiolytic, anticonvulsant, sedative, and analgesic effects. In conclusion, Allopregnanolone-d4 is a useful tool for scientific research in the fields of pharmacokinetics and toxicology. Its stable isotope-labeled properties make it an ideal internal standard for the quantification of Allopregnanolone in biological samples. Its chemical properties and effects on the body make it a fascinating subject of study for researchers in neuroscience and related fields.