2-Methoxyestrone-1,4,16,16 D4

2-Methoxyestrone-1,4,16,16 D4, also known as 2-MeO-E1,4,16,16 D4, is a synthetic estrogen analogue that has four deuterium atoms substituted for four hydrogen atoms in its molecular structure. It is commonly used in research studies as a tracer for measuring the metabolism and distribution of estrone in the body. As an estrogen analogue, 2-MeO-E1,4,16,16 D4 binds to estrogen receptors in the body, which can affect a variety of physiological processes. This includes regulation of the menstrual cycle, bone density, cardiovascular health, and cognitive function. However, its specific effects on the body are still being studied. In terms of chemical information, 2-MeO-E1,4,16,16 D4 has a molecular formula of C19H21D4O3 and a molecular weight of 317.43 g/mol. It is a white to off-white crystalline powder that is soluble in organic solvents such as ethanol and dimethyl sulfoxide. While 2-MeO-E1,4,16,16 D4 is not approved for use as a therapeutic drug, its use in research studies has provided valuable insights into the role of estrone in various physiological processes. Its unique isotopic labeling also allows for precise tracking and quantification of estrone metabolism in the body, making it a useful tool for researchers in the field of endocrinology.