16-Keto-17β-estradiol-2,4,15,15,17-d5

16-Keto-17?-estradiol-2,4,15,15,17-d5 is a stable isotope-labeled estrogen hormone that is commonly used in research studies to investigate the pharmacokinetics and metabolism of estrogen hormones in vivo. This compound is a synthetic derivative of estradiol, the most potent natural estrogen hormone in the human body, and contains five deuterium atoms that are incorporated into the molecule to increase its stability and improve its detection using mass spectrometry. This compound is commonly used as an internal standard in LC-MS/MS assays to accurately quantify endogenous levels of estradiol and its metabolites in biological samples such as blood, urine, and tissue. It can also be used to investigate the pharmacokinetic properties of estrogen hormones in animal models and to study the metabolism and mechanisms of action of these hormones. Chemically, 16-Keto-17?-estradiol-2,4,15,15,17-d5 is a white or off-white crystalline powder with a molecular formula of C18H19D5O3 and a molecular weight of 302.42 g/mol. It has a melting point of 186-188°C and is soluble in organic solvents such as ethanol, methanol, and dimethyl sulfoxide. This compound is stable under normal laboratory conditions and can be stored at -20°C for long-term use.