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(±)-Miconazole-d5 nitrate (2,4-dichlorobenzyloxy-d5) is a deuterated form of miconazole, an antifungal medication used to treat a variety of fungal infections. The deuterated form is primarily used in research and development studies to better understand the pharmacology and efficacy of the drug.
Miconazole works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes. Without ergosterol, the fungal cells are unable to maintain their structure and ultimately die off. Miconazole is effective against a variety of fungal infections including ringworm, athlete's foot, and vaginal yeast infections.
The deuterated form of miconazole, (±)-Miconazole-d5 nitrate (2,4-dichlorobenzyloxy-d5), contains five deuterium atoms which can be used to track the metabolism and distribution of the drug within the body. This information can be used to better understand the pharmacokinetics of the drug and ultimately improve its efficacy and safety.
(±)-Miconazole-d5 nitrate (2,4-dichlorobenzyloxy-d5) is typically administered topically, although it can also be given orally in some cases. The drug is generally well-tolerated with few side effects, although rare cases of allergic reactions have been reported. As with any medication, it is important to follow the dosing instructions provided by your healthcare provider and report any adverse reactions to your doctor.
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