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(±)-Phenoxybenzamine-d5 HCl (benzyl-2,3,4,5,6-d5) is a deuterated form of phenoxybenzamine hydrochloride, which is an alpha-blocker medication used for the treatment of high blood pressure, Raynaud's disease, and pheochromocytoma. This medication works by relaxing the blood vessels to improve blood flow and reduce blood pressure. The deuterated form is used in research and development to study the pharmacokinetics and metabolism of the drug.
The chemical formula of (±)-Phenoxybenzamine-d5 HCl is C18H16D5ClNO, and its molecular weight is 304.8 g/mol. It is a white to off-white crystalline powder that is soluble in water, ethanol, and chloroform.
The deuterated form of phenoxybenzamine hydrochloride is used to study the drug's metabolic pathways and pharmacokinetics in vivo. It is also used in clinical research to investigate the drug's mechanisms of action, drug-drug interactions, and potential side effects. As phenoxybenzamine hydrochloride is a long-acting alpha-blocker, it is important to understand its metabolic fate to determine the optimal dosing regimen and minimize adverse effects.
In conclusion, (±)-Phenoxybenzamine-d5 HCl (benzyl-2,3,4,5,6-d5) is a deuterated form of phenoxybenzamine hydrochloride used in research and development to study the pharmacokinetics and metabolism of the drug.
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