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(±)-Verapamil-d3 HCl (N-methyl-d3) is a deuterated form of Verapamil hydrochloride, a medication used in the treatment of high blood pressure, angina, and certain heart rhythm disorders. Verapamil works by relaxing the blood vessels and reducing the workload on the heart, thus improving blood flow and oxygen supply to the heart.
The deuterated form, (±)-Verapamil-d3 HCl (N-methyl-d3), is used in pharmacokinetic studies to determine the metabolism and pharmacokinetics of Verapamil in the body. It is also used in drug-drug interaction studies and in the development of new drugs. The deuterium labeling in (±)-Verapamil-d3 HCl (N-methyl-d3) enables researchers to distinguish it from non-deuterated Verapamil in the body, thus providing a more accurate assessment of its pharmacokinetics.
Chemically, (±)-Verapamil-d3 HCl (N-methyl-d3) is a hydrochloride salt of Verapamil that contains deuterium atoms at specific locations. It has a molecular formula of C27H34ClN3O4D3 and a molecular weight of 512.12 g/mol. The deuterium atoms in (±)-Verapamil-d3 HCl (N-methyl-d3) replace three hydrogen atoms in the Verapamil molecule.
In conclusion, (±)-Verapamil-d3 HCl (N-methyl-d3) is a deuterated form of Verapamil that is used in pharmacokinetic studies to determine the metabolism and pharmacokinetics of Verapamil in the body. It is an important tool in drug development and drug-drug interaction studies.
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