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4-Methoxy-17β-estradiol-1,2,16,16,17-d5 is a synthetic derivative of the naturally occurring hormone, estradiol. It is a potent estrogen receptor antagonist, meaning that it blocks the effects of estrogen in the body. This compound has been studied for its potential use in cancer treatment, particularly in the treatment of hormone-sensitive cancers such as breast and prostate cancer.
Chemically, 4-Methoxy-17β-estradiol-1,2,16,16,17-d5 is a modified version of estradiol, with five deuterium atoms incorporated into the molecule. Deuterium is a heavy isotope of hydrogen, which can be used in the synthesis of labeled compounds for research purposes.
In terms of usage, 4-Methoxy-17β-estradiol-1,2,16,16,17-d5 is primarily used as a research tool in the study of estrogen receptor signaling pathways and the development of new cancer therapies. It is not approved for use in humans, and its potential therapeutic applications are still being investigated.
Overall, 4-Methoxy-17β-estradiol-1,2,16,16,17-d5 is a valuable tool for researchers studying the role of estrogen in cancer development and treatment. Its unique chemical properties make it a useful tool for labeled compound synthesis, and its potential therapeutic applications may lead to the development of new and more effective cancer treatments in the future.
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