Atorvastatin D5 sodium
| Product Name | Atorvastatin D5 sodium |
|---|---|
| Alternate Names | Atorvastatin Stable Isotopes, Stable Isotopes of Atorvastatin |
| CAT No. | CS-CV-00005 |
| CAS No. | 134523-01-6 (Unlabelled) |
| Category | Stable Isotopes |
| Stock | Enquire |
| Mol. Wt. | 586.66 g/mol |
| Mol. For. | C33H30D5FN2NaO5 |
| Hazardous | This is not a Hazardous Compound |
| COA | View Sample COA |
| MSDS | View Sample MSDS |
| Parent API | Atorvastatin |
| Therapeutic | Anti-Diabetic |
| Smileys | CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.[Na+] |
| Canonical Smiles | CC(C)C1=C(C(=C(N1CCC(CC(CC(=O)[O-])O)O)C2=CC=C(C=C2)F)C3=CC=CC=C3)C(=O)NC4=CC=CC=C4.[Na+] |
| InchIKey | VVRPOCPLIUDBSA-CNZCJKERSA-M |
| Inchl | InChI=1S/C33H35FN2O5.Na/c1-21(2)31-30(33(41)35-25-11-7-4-8-12-25)29(22-9-5-3-6-10-22)32(23-13-15-24(34)16-14-23)36(31)18-17-26(37)19-27(38)20-28(39)40;/h3-16,21,26-27,37-38H,17-20H2,1-2H3,(H,35,41)(H,39,40);/q;+1/p-1/t26-,27-;/m1./s1 |
| IUPAC | sodium;(3R,5R)-7-[2-(4-fluorophenyl)-3-phenyl-4-(phenylcarbamoyl)-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate |
| Controlled | No |
| Shipping | Free for purchase above 1000$ |
| Delivery | In-Stock, products will be dispatched within 24 hours via FedEx for USA, Europe, and other countries. |
| Return | Returns/replacement accepted if you are not satisfied with the quality of the product, (please send us an email with the reason/issues which are facing, within 15 days, after receipt of the product). |
| Ordering | Place your order online or by email sales@clearsynth.com |
Atorvastatin D5 sodium is a deuterated form of the drug atorvastatin sodium. Atorvastatin sodium is a selective and competitive inhibitor of HMG-CoA reductase, an enzyme that catalyzes the conversion of HMG-CoA to mevalonate, an important precursor of cholesterol biosynthesis. Atorvastatin D5 sodium is identical in mechanism of action to atorvastatin sodium, but has five deuterium atoms substituted for five hydrogen atoms in the molecular structure. This substitution provides a unique tracer for drug metabolism studies.
Atorvastatin D5 sodium is commonly used in pharmacokinetic studies to determine the metabolic fate of atorvastatin. It is administered orally and undergoes extensive hepatic metabolism. The deuterium substitution in atorvastatin D5 sodium allows for the precise measurement of drug concentrations and metabolite formation in various tissues and fluids throughout the body. This information can be used to determine the pharmacokinetic properties of the drug, such as absorption, distribution, metabolism, and excretion.
Overall, Atorvastatin D5 sodium is a valuable tool in drug metabolism studies, providing important insights into the pharmacokinetics of atorvastatin and aiding in the development of new drugs with similar mechanisms of action.
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Related Compounds
Atorvastatin D5 calcium | Atorvastatin D5 | Atorvastatin D5 4-(phenyl-d5) Lactone | Atorvastatin sodium salt 13C6 | Atorvastatin-d5 (N-(phenyl-d5) Lactone | p-Hydroxyatorvastatin 13C6 |