Aliskiren D3

Aliskiren D3 is a deuterated form of the drug Aliskiren, which is used to treat hypertension or high blood pressure. This medication is an orally active, non-peptide renin inhibitor that works by blocking the activity of renin, an enzyme produced by the kidneys that helps regulate blood pressure. By inhibiting renin, Aliskiren D3 helps to relax blood vessels, thereby lowering blood pressure and reducing the risk of heart attack, stroke, and other cardiovascular diseases. Chemically, Aliskiren D3 is a white to off-white powder that is soluble in water and has a molecular weight of 621.80 g/mol. The deuterium atoms in the molecule are used to increase the stability and bioavailability of the drug, making it more effective and longer-lasting than the non-deuterated form. Its chemical formula is C30H53N3O6D3, and its IUPAC name is (2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethylpropyl)-4-hydroxy-2,7-diisopropyl-8-[4-methoxy-3-(3-methoxypropoxy)phenyl]-octanamide-3,3,7,7-tetradeuterio-4,4-diacid. Aliskiren D3 is typically taken once a day, with or without food, and the dosage may vary depending on the severity of the patient's condition. It is important to follow the instructions of a healthcare professional when taking this medication, as it may interact with other drugs and cause side effects such as diarrhea, cough, and headache.