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Ambrisentan acyl-β-D-glucuronide D10

Chemical Name Ambrisentan acyl-β-D-glucuronide D10
CAT No. CS-CX-00082
CAS Registry# 1106685-58-8 (Unlabeled)
Status Under Certification (Usually dispatched in 5 days)
Category Stable Isotopes
Hazardous This is not a Hazardous Compound
COA View Sample COA
Controlled No

Additional Information


Controlled No
Parent API Ambrisentan
Smileys COC([C@@H](C(O[C@@H]([C@@H]([C@@H](O)[C@@H]1O)O)O[C@@H]1C(O)=O)=O)OC2=NC(C)=CC(C)=N2)(C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H]
Hazardous No


Usage and description


Ambrisentan acyl-β-D-glucuronide D10 is a metabolite of the drug Ambrisentan, which is a medication used to treat pulmonary arterial hypertension (PAH). This metabolite is formed in the liver when Ambrisentan is broken down and is excreted in the urine. Chemically, Ambrisentan acyl-β-D-glucuronide D10 is a glucuronide conjugate of Ambrisentan, which means that it has been modified by the addition of a glucuronic acid molecule. This modification makes the compound more water-soluble and easier for the body to excrete. In terms of usage, Ambrisentan acyl-β-D-glucuronide D10 is not used therapeutically, but instead serves as a marker for the presence of Ambrisentan in the body. It is commonly measured in urine samples as a way to monitor patient compliance with Ambrisentan therapy and to assess the drug's pharmacokinetics. While Ambrisentan acyl-β-D-glucuronide D10 is generally considered to be a harmless metabolite, it is important to note that all drugs have the potential for side effects. Patients taking Ambrisentan should be monitored for any adverse reactions, and any concerns should be discussed with a healthcare provider. Overall, Ambrisentan acyl-β-D-glucuronide D10 plays an important role in the management of PAH and in ensuring the safe and effective use of Ambrisentan as a medication.

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