A    B    C    D    E    F    G    H    I    J    K    L    M    N    O    P    Q    R    S    T    U    V    W    X    Y    Z    

Amlodipine D4

Chemical Name Amlodipine D4
CAT No. CS-CX-00109
CAS No. 1185246-14-3
Status Available for Immediate Dispatch
Category Stable Isotopes
Mol. Wt. 412.90 mol/g
Mol. For. C₂₀H₂₁D₄ClN₂O₅
Hazardous This is a Hazardous Compound
COA View Sample COA

Additional Information

Packing Product will be supplied in Vials, in certain conditions we also use 'Septa Vials'
Controlled No
Parent API Amlodipine
Smileys CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
Canonical Smiles CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
Inchl InChI=1S/C20H25ClN2O5/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21/h5-8,17,23H,4,9-11,22H2,1-3H3/i9D2,10D2
IUPAC 3-O-ethyl 5-O-methyl 2-[(2-amino-1,1,2,2-tetradeuterioethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate
Hazardous Yes

Usage and description

Amlodipine D4 is a deuterated form of amlodipine, a commonly used medication for the treatment of hypertension and angina. Amlodipine D4 has the same chemical structure as amlodipine, but with four deuterium atoms replacing four hydrogen atoms. This modification is done for research purposes, as it allows for more accurate analysis of drug metabolism and pharmacokinetics. Amlodipine D4 works by inhibiting the influx of calcium ions into smooth muscle cells, leading to vasodilation and relaxation of the blood vessels. This results in a decrease in blood pressure and improved blood flow to the heart. Amlodipine D4 has a long half-life of approximately 30-50 hours, allowing for once-daily dosing. Amlodipine D4 is typically administered orally in tablet form and is available in various strengths. The dosing regimen will depend on the patient's age, medical history, and the severity of their condition. Amlodipine D4 is generally well-tolerated, with common side effects including dizziness, headache, and swelling in the ankles and feet. In conclusion, Amlodipine D4 is a deuterated form of amlodipine that is used for research purposes to better understand the pharmacokinetics and metabolism of the drug. It works by inhibiting calcium influx, leading to vasodilation and a decrease in blood pressure. Amlodipine D4 is typically administered orally and is well-tolerated, with common side effects including dizziness and headache.

This page contains information about Amlodipine D4. You can buy Amlodipine D4 from Clearsynth at best competitive price with assured price guarantee. Clearsynth offers best quality Amlodipine D4