Asunaprevir D9

Product Name Asunaprevir D9
CAT No. CS-CX-00135
CAS No. 630420-16-5 (Unlabeled)
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Smileys O=C([C@H](C[C@@H](OC1=NC=C(OC)C2=C1C=C(Cl)C=C2)C3)N3C([C@H](C(C)(C)C)NC(OC(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)=O)N[C@]4([C@H](C=C)C4)C(N[S](=O)(C5CC5)=O)=O
Canonical Smiles CC(C)(C)C(C(=O)N1CC(CC1C(=O)NC2(CC2C=C)C(=O)NS(=O)(=O)C3CC3)OC4=NC=C(C5=C4C=C(C=C5)Cl)OC)NC(=O)OC(C)(C)C
InchIKey XRWSZZJLZRKHHD-WVWIJVSJSA-N
Inchl InChI=1S/C35H46ClN5O9S/c1-9-19-16-35(19,31(44)40-51(46,47)22-11-12-22)39-28(42)25-15-21(49-29-24-14-20(36)10-13-23(24)26(48-8)17-37-29)18-41(25)30(43)27(33(2,3)4)38-32(45)50-34(5,6)7/h9-10,13-14,17,19,21-22,25,27H,1,11-12,15-16,18H2,2-8H3,(H,38,45)(H,39,42)(H,40,44)/t19-,21-,25+,27-,35-/m1/s1
IUPAC tert-butyl N-[(2S)-1-[(2S,4R)-4-(7-chloro-4-methoxyisoquinolin-1-yl)oxy-2-[[(1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-ethenylcyclopropyl]carbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]carbamate
Controlled No
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Asunaprevir D9 is a deuterated version of the hepatitis C virus (HCV) protease inhibitor Asunaprevir. It is used in the treatment of chronic HCV genotype 1 infection, either alone or in combination with other antiviral medications. Asunaprevir D9 works by inhibiting the activity of the NS3/4A protease, which is essential for viral replication, thus preventing the virus from spreading and causing further damage to the liver. Asunaprevir D9 is a small molecule with a molecular weight of 725.9 g/mol. It is a prodrug that is converted to the active form, Asunaprevir, once it enters the body. The deuterium substitution in Asunaprevir D9 provides several advantages, including increased stability, improved pharmacokinetics, and reduced drug-drug interactions. The recommended dosage of Asunaprevir D9 varies depending on the patient's medical history, HCV genotype, and treatment history. It is administered orally, usually as a single tablet once a day, with or without food. It is important to follow the prescribed dosage and duration of treatment to achieve the best results. Like all medications, Asunaprevir D9 may cause side effects, including headache, fatigue, nausea, and diarrhea. It may also interact with other medications, so it is important to inform your healthcare provider of any other medications you are taking before starting treatment with Asunaprevir D9. In conclusion, Asunaprevir D9 is an effective medication for the treatment of chronic HCV genotype 1 infection. Its deuterium substitution provides several advantages, making it a preferred option for patients who require long-term treatment. However, it should only be used under the guidance and supervision of a qualified healthcare provider.

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