2-Demecolchicine D3

Product Name 2-Demecolchicine D3
Alternate Names Colchicine Stable Isotopes, Stable Isotopes of Colchicine
CAT No. CS-CX-00282
CAS No. 1217630-52-8
Category Stable Isotopes
Stock Enquire
Mol. Wt. Not Available
Mol. For. Not Available
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Colchicine
Smileys COC(C(O)=C(OC)C=C1CC[C@H](NC(C([2H])([2H])[2H])=O)C2=C3)=C1C2=CC=C(OC)C3=O
Canonical Smiles CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)O)OC
InchIKey DPOVAJCRYIUTBD-VSLDJYOXSA-N
Inchl InChI=1S/C21H23NO6/c1-11(23)22-15-7-5-12-9-18(27-3)20(25)21(28-4)19(12)13-6-8-17(26-2)16(24)10-14(13)15/h6,8-10,15,25H,5,7H2,1-4H3,(H,22,23)/t15-/m0/s1/i1D3
IUPAC 2,2,2-trideuterio-N-[(7S)-2-hydroxy-1,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
Controlled No
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2-Demecolchicine D3 is a chemical compound that is used in research laboratories to study the effects of colchicine, a natural compound extracted from the autumn crocus plant. 2-Demecolchicine D3 is a deuterated version of Demecolchicine, which is a synthetic derivative of colchicine. The addition of deuterium to the molecule allows for more precise analysis using techniques such as nuclear magnetic resonance (NMR) spectroscopy. 2-Demecolchicine D3 is often used in research studies to understand the mechanism of action of colchicine, which has been used for centuries as an anti-inflammatory and anti-tumor agent. Colchicine works by binding to tubulin, a protein involved in cell division, and inhibiting its function. This leads to disruption of the cell cycle and ultimately cell death. 2-Demecolchicine D3 is used to study the binding of colchicine to tubulin, and the effect of deuterium substitution on this interaction. In addition to its use in research, 2-Demecolchicine D3 has potential applications in the pharmaceutical industry. Colchicine and its derivatives have been investigated as potential treatments for a variety of conditions, including gout, cancer, and Alzheimer's disease. 2-Demecolchicine D3 may offer advantages over traditional colchicine derivatives, such as increased stability and improved pharmacokinetics. However, further research is needed to fully understand the potential benefits of this compound.

Related Compounds

Colchicine 13C D3 | Colchicine D3 | iso-Colchicine-d3 | Colchicine D6 |

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