Arterolane-D6

Arterolane-D6 is a deuterium-labeled version of the drug Arterolane, which is an antimalarial medication used to treat and prevent malaria caused by Plasmodium falciparum, one of the deadliest strains of the malaria parasite. Arterolane-D6 is a synthetic compound that belongs to the arylaminoalcohol class of antimalarial drugs. The mechanism of action of Arterolane-D6 involves inhibiting the heme detoxification pathway in the malaria parasite, which leads to the accumulation of toxic heme in the parasite's digestive vacuole and ultimately causes its death. Arterolane-D6 has been shown to have a high efficacy against drug-resistant strains of Plasmodium falciparum, making it a promising candidate for the treatment and prevention of malaria. In terms of chemical information, Arterolane-D6 has a molecular formula of C19H21D6ClN4O2 and a molecular weight of 368.95 g/mol. It is a white to off-white crystalline powder that is soluble in water and ethanol. Arterolane-D6 is typically administered orally in the form of tablets or capsules, with a recommended dosage of 150mg once daily for three days. Overall, Arterolane-D6 is a potent and effective antimalarial drug that offers hope in the fight against malaria, particularly in regions where drug-resistant strains of the parasite are prevalent.