6-Thioguanine 13C3 15N

6-Thioguanine 13C3 15N is a modified version of the drug 6-thioguanine, which is commonly used to treat leukemia. This particular version of the drug is labeled with three carbon-13 isotopes and one nitrogen-15 isotope, which allows researchers to track its movement through the body and study its effects on cells. The chemical structure of 6-Thioguanine 13C3 15N is similar to that of guanine, one of the four nucleotide bases that make up DNA. However, the addition of a sulfur atom to the structure gives it unique properties that allow it to interfere with the replication of cancer cells. Specifically, 6-thioguanine works by incorporating itself into the DNA of cancer cells and disrupting the normal processes of cell division. The use of 6-thioguanine in cancer treatment is based on its ability to selectively kill cancer cells while leaving healthy cells relatively unaffected. However, the drug can have some serious side effects, including bone marrow suppression and an increased risk of infection. For this reason, it is typically used only in cases where other treatments have failed or are not effective. Overall, the use of 6-Thioguanine 13C3 15N is an important tool in both basic research and clinical studies of cancer treatment. Its unique chemical properties and labeled isotopes allow for precise tracking of its effects on cells, which can help researchers develop new and more effective treatments for cancer in the future.