Treosulfan D4

Product Name Treosulfan D4
CAT No. CS-CX-00620
CAS No. 299-75-2 (Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 282.33 g/mol
Mol. For. C₆H₁₀D₄O₈S₂
Hazardous This is not a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Purity Not specified
Smileys O[C@@H](C([2H])([2H])O[S](C)(=O)=O)[C@@H](O)C([2H])([2H])O[S](C)(=O)=O
Canonical Smiles CS(=O)(=O)OCC(C(COS(=O)(=O)C)O)O
InchIKey YCPOZVAOBBQLRI-WDSKDSINSA-N
Inchl InChI=1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3/t5-,6-/m0/s1
IUPAC [(2S,3S)-2,3-dihydroxy-4-methylsulfonyloxybutyl] methanesulfonate
Controlled No
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Treosulfan D4 is a deuterated derivative of the chemotherapeutic agent Treosulfan. It is a prodrug that is activated in vivo to produce active metabolites that exhibit cytotoxic activity. Treosulfan D4 is used in the treatment of various types of cancer including ovarian, breast, and lung cancer. The mechanism of action of Treosulfan D4 involves the formation of DNA cross-links, which inhibit DNA replication and transcription, leading to apoptosis. The deuterated form of the drug is believed to exhibit increased efficacy and reduced toxicity compared to the non-deuterated form due to its altered pharmacokinetics. Treosulfan D4 is administered intravenously and is typically used in combination with other chemotherapeutic agents. The dosage and duration of treatment depend on the patient's condition and response to therapy. In terms of chemical information, Treosulfan D4 has a molecular formula of C7H6D4O6S2 and a molecular weight of 298.35 g/mol. It is a white or off-white crystalline powder that is soluble in water and methanol. The drug is stable under normal storage conditions and should be stored in a cool, dry place away from light and moisture. Overall, Treosulfan D4 is an important chemotherapeutic agent used in the treatment of various types of cancer. Its unique deuterated structure provides improved efficacy and reduced toxicity, making it a valuable addition to the arsenal of cancer therapies.

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