Topiroxostat-D4

Product Name Topiroxostat-D4
Alternate Names Topiroxostat Stable Isotopes, Stable Isotopes of Topiroxostat
CAT No. CS-CX-00752
CAS No. 577778-58-6 (Unlabeled)
Category Stable Isotopes
Stock IN-Stock
Mol. Wt. 252.27 g/mol
Mol. For. C₁₃H₄D₄N₆
Hazardous This is a Hazardous Compound
COA View Sample COA
MSDS View Sample MSDS
Parent API Topiroxostat
Smileys N#CC1=CC(C2=NN=C(C3=C([2H])C([2H])=NC([2H])=C3[2H])N2)=CC=N1
Canonical Smiles C1=CN=CC=C1C2=NC(=NN2)C3=CC(=NC=C3)C#N
InchIKey UBVZQGOVTLIHLH-UHFFFAOYSA-N
Inchl InChI=1S/C13H8N6/c14-8-11-7-10(3-6-16-11)13-17-12(18-19-13)9-1-4-15-5-2-9/h1-7H,(H,17,18,19)
IUPAC 4-(5-pyridin-4-yl-1H-1,2,4-triazol-3-yl)pyridine-2-carbonitrile
Controlled No
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Topiroxostat-D4 is a deuterated version of Topiroxostat, a medication used to treat hyperuricemia in patients with gout. Hyperuricemia is a condition that occurs when there is an excess of uric acid in the blood, which can lead to the formation of urate crystals in the joints, causing pain and inflammation. Topiroxostat-D4 works by inhibiting the enzyme xanthine oxidase, which is responsible for the production of uric acid in the body. By reducing the levels of uric acid in the blood, Topiroxostat-D4 helps to prevent the formation of urate crystals in the joints, thereby reducing the risk of gout attacks. Chemically, Topiroxostat-D4 is a deuterated analog of Topiroxostat, meaning that it contains four deuterium atoms in place of four hydrogen atoms. Deuterium is a stable isotope of hydrogen that has a slightly higher mass, which can affect the pharmacokinetics of the drug. Deuterated drugs have been shown to have improved metabolic stability, longer half-lives, and reduced toxicity compared to their non-deuterated counterparts. In terms of usage, Topiroxostat-D4 is typically administered orally in the form of tablets. The recommended dosage may vary depending on the patient's age, weight, and medical history. It is important to follow the dosage instructions provided by a healthcare professional to ensure the safe and effective use of the medication.

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